CAJ | 학술논문

目的：探讨机械通气联合蛇毒血凝酶治疗新生儿肺出血的临床疗效。方法选取40例新生儿肺出血患儿作为研究对象，随机分为观察组和对照组，分别采用机械通气联合肾上腺素盐水和机械通气联合蛇毒血凝酶治疗，观察两组患者的治疗疗效。结果观察组机械通气时间、肺出血停止时间均明显少于对照组（ P＜0.05）；两组患儿均未发生过敏反应、血栓及器官功能性损伤疾病等，对照组患儿1例死亡，观察组无死亡病例。结论机械通气联合蛇毒血凝酶可以有效治疗新生儿肺出血，具有临床应用及推广价值。
목적：탐토궤계통기연합사독혈응매치료신생인폐출혈적림상료효。방법선취40례신생인폐출혈환인작위연구대상，수궤분위관찰조화대조조，분별채용궤계통기연합신상선소염수화궤계통기연합사독혈응매치료，관찰량조환자적치료료효。결과관찰조궤계통기시간、폐출혈정지시간균명현소우대조조（ P＜0.05）；량조환인균미발생과민반응、혈전급기관공능성손상질병등，대조조환인1례사망，관찰조무사망병례。결론궤계통기연합사독혈응매가이유효치료신생인폐출혈，구유림상응용급추엄개치。
Objective To investigate the clinical efficacy of condensing enzymetreatment of neo-natal pulmonary hemorrhage mechanical ventilation combined with venom blood.Methods 40 cases of neonatal pulmonar were selected from our hospital in 2013,and randomly divided into observation group and control group which were treated with mechanical ventilation combined with adrenaline and mechanical ventilation combined with hemocoagulase respectively.Then the effects were observed.Results The mechanical ventilation time and pulmonary haemorrhage stop time were (1.16±0.47) d and (3.66 ±1.23) d repsectively in observation group,while those for the control group were (2.00 ±0.67) d and (5.17 ±1.55) d., which was significantly different ( P<0.05);Two groups of children did not have allergic reaction, thrombosis, and or-gan functional injury diseases, etc..There was 1 case of death in the control group, while there was none in observation group.Conclusion It is effective to combine mechanical ventilation with hemocoagulasecan in the treatment of neonatal pulmonary hemorrhage.