华西口腔医学杂志
華西口腔醫學雜誌
화서구강의학잡지
WEST CHINA JOURNAL OF STOMATOLOGY
2014年
6期
578-580
,共3页
腭裂%听觉诱发电位%事件相关电位%中枢听觉神经系统
腭裂%聽覺誘髮電位%事件相關電位%中樞聽覺神經繫統
악렬%은각유발전위%사건상관전위%중추은각신경계통
cleft palate%auditory evoked potential%event related potential%central auditory nervous system
目的：??采用测试听觉诱发电位和事件相关电位（ERP）的方法，了解腭裂患儿的中枢听觉神经系统功能。方法??以34名非综合征型腭裂患者为研究对象，记录儿童的听觉脑干诱发电位（ABR）、中潜伏期诱发电位（MLR）和ERP中的负失配电位成分（MMN），并与正常同龄儿童相比较。结果??与正常儿童相比，腭裂儿童的MMN反应明显较弱（F=227.69，P<0.01）；而腭裂儿童的ABR、MLR与正常儿童相比无统计学差异（P>0.05）。结论??腭裂儿童的中枢听觉神经系统存在功能障碍，主要表现为大脑听觉皮层水平的听觉处理功能障碍，而脑干和皮层下水平的听觉感知功能基本正常。
目的：??採用測試聽覺誘髮電位和事件相關電位（ERP）的方法，瞭解腭裂患兒的中樞聽覺神經繫統功能。方法??以34名非綜閤徵型腭裂患者為研究對象，記錄兒童的聽覺腦榦誘髮電位（ABR）、中潛伏期誘髮電位（MLR）和ERP中的負失配電位成分（MMN），併與正常同齡兒童相比較。結果??與正常兒童相比，腭裂兒童的MMN反應明顯較弱（F=227.69，P<0.01）；而腭裂兒童的ABR、MLR與正常兒童相比無統計學差異（P>0.05）。結論??腭裂兒童的中樞聽覺神經繫統存在功能障礙，主要錶現為大腦聽覺皮層水平的聽覺處理功能障礙，而腦榦和皮層下水平的聽覺感知功能基本正常。
목적：??채용측시은각유발전위화사건상관전위（ERP）적방법，료해악렬환인적중추은각신경계통공능。방법??이34명비종합정형악렬환자위연구대상，기록인동적은각뇌간유발전위（ABR）、중잠복기유발전위（MLR）화ERP중적부실배전위성분（MMN），병여정상동령인동상비교。결과??여정상인동상비，악렬인동적MMN반응명현교약（F=227.69，P<0.01）；이악렬인동적ABR、MLR여정상인동상비무통계학차이（P>0.05）。결론??악렬인동적중추은각신경계통존재공능장애，주요표현위대뇌은각피층수평적은각처리공능장애，이뇌간화피층하수평적은각감지공능기본정상。
Objective We aim to explore the central auditory nervous system (CANS) functioning in children with nonsyndromic cleft palates by analyzing the auditory evoked potentials and event-related potentials (ERP). Methods A total of 34 children with nonsyndromic cleft palates were recruited as subjects, and 27 normally developed children were selected as the normal controls. Auditory brainstem response (ABR), middle latency response (MLR), and mismatch negativity (MMN) of ERP were selected as indices to observe the function of CANS in children in both groups. Results Astatistically significant difference between the groups was obtainedin the MMN recording (F=227.69, P<0.01), whereas no significant group differences were obtained in the ABR and MLR results (P>0.05). Children with nonsyndromic cleft palates showed diminished MMN responses compared with the normal controls, whereas ABR and MLR were within the normal range. Conclusion Children with nonsyndromic cleft palates are at risk of central auditory discrimination dysfunction. The significant abnormal eventrelated potentials recorded in children with cleft palates suggest that the dysfunction of CANS maybe located at the cortical level and normal function of CANS was located at the brain stem and sub-cortical level.
