中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
36期
152-153,155
,共3页
高血压%左心室构型%血浆BNP
高血壓%左心室構型%血漿BNP
고혈압%좌심실구형%혈장BNP
Hypertension%Left ventricular geometry%Plasma BNP
目的：对高血压患者不同左室构型的结构和功能变化与血浆BNP的相关因素进行分析，以提高对高血压患者早期引起心肌损害加重的相关因素的重视。方法：收治高血压患者86例，根据不同的心肌质量指数，分为左室壁非肥厚组(A组)和左室壁肥厚组(B组)。收治正常人30例作对照组(N组)，分别记录其基本临床资料，与超声心动图各项指标一起作为影响BNP的因子进行统计分析。结果：①高血压较对照组，且高血压A、B组间BNP水平、收缩压、舒张压对比差异有统计学意义(P＜0.05)；②超声各参数比较：A、B两组与对照组比较，LAVI、E峰、A峰、E/A、E'峰、E/E'差异均有统计学意义(P＜0.05)；B 组与对照组比较，LVWI、IVS、LVPW 差异有统计学意义(P＜0.05)；A、B 组间LVWI、IVS、LVPW、LAVI对比组间差异有统计学意义(P＜0.05)。③BNP与患者年龄、高血压病程、LVED、LVEF等无明显相关性，而与 IVS、LVPW、LVMI 和 LVAI 呈正相关(r=0.316，P＜0.05；r=0.471，P＜0.001；r=0.637，P＜0.001；r=0.462，P＜0.005)。结论：在左室收缩功能正常的高血压患者中存在不同程度的舒张功能减低和心肌损害，心肌损害程度与左室壁厚度及左房容积指数相关，在高血压的随访过程中，应对这些相关因素引起重视，及时给予治疗。
目的：對高血壓患者不同左室構型的結構和功能變化與血漿BNP的相關因素進行分析，以提高對高血壓患者早期引起心肌損害加重的相關因素的重視。方法：收治高血壓患者86例，根據不同的心肌質量指數，分為左室壁非肥厚組(A組)和左室壁肥厚組(B組)。收治正常人30例作對照組(N組)，分彆記錄其基本臨床資料，與超聲心動圖各項指標一起作為影響BNP的因子進行統計分析。結果：①高血壓較對照組，且高血壓A、B組間BNP水平、收縮壓、舒張壓對比差異有統計學意義(P＜0.05)；②超聲各參數比較：A、B兩組與對照組比較，LAVI、E峰、A峰、E/A、E'峰、E/E'差異均有統計學意義(P＜0.05)；B 組與對照組比較，LVWI、IVS、LVPW 差異有統計學意義(P＜0.05)；A、B 組間LVWI、IVS、LVPW、LAVI對比組間差異有統計學意義(P＜0.05)。③BNP與患者年齡、高血壓病程、LVED、LVEF等無明顯相關性，而與 IVS、LVPW、LVMI 和 LVAI 呈正相關(r=0.316，P＜0.05；r=0.471，P＜0.001；r=0.637，P＜0.001；r=0.462，P＜0.005)。結論：在左室收縮功能正常的高血壓患者中存在不同程度的舒張功能減低和心肌損害，心肌損害程度與左室壁厚度及左房容積指數相關，在高血壓的隨訪過程中，應對這些相關因素引起重視，及時給予治療。
목적：대고혈압환자불동좌실구형적결구화공능변화여혈장BNP적상관인소진행분석，이제고대고혈압환자조기인기심기손해가중적상관인소적중시。방법：수치고혈압환자86례，근거불동적심기질량지수，분위좌실벽비비후조(A조)화좌실벽비후조(B조)。수치정상인30례작대조조(N조)，분별기록기기본림상자료，여초성심동도각항지표일기작위영향BNP적인자진행통계분석。결과：①고혈압교대조조，차고혈압A、B조간BNP수평、수축압、서장압대비차이유통계학의의(P＜0.05)；②초성각삼수비교：A、B량조여대조조비교，LAVI、E봉、A봉、E/A、E'봉、E/E'차이균유통계학의의(P＜0.05)；B 조여대조조비교，LVWI、IVS、LVPW 차이유통계학의의(P＜0.05)；A、B 조간LVWI、IVS、LVPW、LAVI대비조간차이유통계학의의(P＜0.05)。③BNP여환자년령、고혈압병정、LVED、LVEF등무명현상관성，이여 IVS、LVPW、LVMI 화 LVAI 정정상관(r=0.316，P＜0.05；r=0.471，P＜0.001；r=0.637，P＜0.001；r=0.462，P＜0.005)。결론：재좌실수축공능정상적고혈압환자중존재불동정도적서장공능감저화심기손해，심기손해정도여좌실벽후도급좌방용적지수상관，재고혈압적수방과정중，응대저사상관인소인기중시，급시급여치료。
Objective:To explore the related factors of the changes of structure and function of different patterns of left ventricular geometry in hypertensive patients and plasma BNP,in order to improve the attention of the related factors to early aggravate myocardial damage in hypertensive patients.Methods:86 hypertension patients were selected.According to the different myocardial mass index,they were divided into the left ventricular non hypertrophy group(A group) and left ventricular hypertrophy group(B group).30 cases of normal people were selected as the control group(N group).We recorded the basic clinical information, together with the ultrasonic Beckoning maps for each index,and they were as the impact of the factors of BNP with statistical analysis.Results: ① Compared the hypertension group and the control group,and compared the hypertension A group and hypertension B group,the difference in the BNP level,systolic pressure and diastolic pressure was significant(P<0.05). ②Comparison of various ultrasonic parameters:A and B group compared with the control group,there were statistical difference in LAVI,E peak,A peak,E/A peak,E',E/E';B group compared with the control group,there were significant difference in LVWI,IVS, LVPW;A group compared with B group,there were significant difference in IVS,LVWI,LVPW,LAVI(P<0.05). ③ BNP had no significant correlation with the patient's age,duration of hypertension,LVED and LVEF,but was positively correlated with IVS, LVPW,LVMI and LVAI(r=0.316,P<0.05;r=0.471,P<0.001;r=0.637,P<0.001;r=0.462,P<0.005).Conclusion:In the patients with hypertension with normal left ventricular systolic function,there were varying degrees of diastolic dysfunction and myocardial injury,myocardial damage was associated with left ventricular wall thickness and left atrial volume index.In the follow-up process of hypertension,we should pay attention to these factors,and give timely treatment.
