化学通报（网络版）
化學通報（網絡版）
화학통보（망락판）
Chemistry Online
2014年
1期
1-12
,共12页
汪震%郑土才%潘向军%王兵%梅念%郑建霖%聂孝文
汪震%鄭土纔%潘嚮軍%王兵%梅唸%鄭建霖%聶孝文
왕진%정토재%반향군%왕병%매념%정건림%섭효문
Gabriel反应%邻苯二甲酰亚胺%伯胺%水合肼%二甲基海因%合成
Gabriel反應%鄰苯二甲酰亞胺%伯胺%水閤肼%二甲基海因%閤成
Gabriel반응%린분이갑선아알%백알%수합정%이갑기해인%합성
Gabriel reaction%Phthalimide%Primary amine%Hydrazine hydrate%Dimethylhydantoin%Synthesis
本文先简单介绍了Gabriel反应，然后分别综述了苄位和烯丙位等活泼卤代烃、伯卤代烃、磺酸酯的Gabriel反应，邻苯二甲酰亚胺与环氧化合物的缩合、含邻苯二甲酰亚胺基的合成子、邻苯二甲酰亚胺与醇在 Mitsunobu 条件下的直接 Gabriel 反应等，最后对 Gabriel 反应的应用进行了总结和展望。指出应加强对Gabriel反应的系统研究，特别是脱邻苯二甲酰基的方法和基于Gabriel反应原理的替代方法的研究。
本文先簡單介紹瞭Gabriel反應，然後分彆綜述瞭芐位和烯丙位等活潑滷代烴、伯滷代烴、磺痠酯的Gabriel反應，鄰苯二甲酰亞胺與環氧化閤物的縮閤、含鄰苯二甲酰亞胺基的閤成子、鄰苯二甲酰亞胺與醇在 Mitsunobu 條件下的直接 Gabriel 反應等，最後對 Gabriel 反應的應用進行瞭總結和展望。指齣應加彊對Gabriel反應的繫統研究，特彆是脫鄰苯二甲酰基的方法和基于Gabriel反應原理的替代方法的研究。
본문선간단개소료Gabriel반응，연후분별종술료변위화희병위등활발서대경、백서대경、광산지적Gabriel반응，린분이갑선아알여배양화합물적축합、함린분이갑선아알기적합성자、린분이갑선아알여순재 Mitsunobu 조건하적직접 Gabriel 반응등，최후대 Gabriel 반응적응용진행료총결화전망。지출응가강대Gabriel반응적계통연구，특별시탈린분이갑선기적방법화기우Gabriel반응원리적체대방법적연구。
This paper first introduced Gabriel reaction firstly, then discussed in order Gabriel reactions of active halides such as benzyl-and allyl-halides, primary halides, and sulfonates, Gabriel reactions of phthalimide with epoxy compounds, phthalimide-containing synthons, and direct reaction of phthalimide with alcohols under Mitsunobu conditions, and finally summarized and overviewed the development of Gabriel reaction. It was pointed out that further and systematic studies for Gabriel reaction and particularly methods for the removal of the phthalimide functionality and replacement methods based on Gabriel reaction principles are clearly needed.
