中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
6期
1062-1065
,共4页
刘静%农铮%邱萍%覃海研%关海滨%刘成娟%张玉%林墨菊
劉靜%農錚%邱萍%覃海研%關海濱%劉成娟%張玉%林墨菊
류정%농쟁%구평%담해연%관해빈%류성연%장옥%림묵국
围产儿%出生缺陷%监测%流行特征
圍產兒%齣生缺陷%鑑測%流行特徵
위산인%출생결함%감측%류행특정
perinatal infant%birth defects%monitoring%epidemiological feature
目的：了解柳州市出生缺陷发生的变化趋势及流行病学特征，为开展出生缺陷病因研究及制订出生缺陷综合干预措施提供参考依据。方法对2009～2013年柳州市范围内119家助产医院的围产儿出生缺陷监测资料进行统计分析。结果5年共监测围产儿239343例，发现出生缺陷儿4324例，出生缺陷总发生率为18．07‰，整体呈现上升趋势（χ2趋势＝44．393，P＜0．001）。出生缺陷发生率前5位顺位依次是先天性心脏病、多指／趾、外耳其他畸形、总唇裂、马蹄内翻足。缺陷发生率城镇（22．36‰）高于农村（14．94‰，（χ2＝194．909，P＜0．001）；男性（20．34‰）高于女性（15．33‰）（χ2＝84．584，P＜0．001）。结论柳州市出生缺陷发生率处于较高水平，应有针对性的进一步加大出生缺陷的一、二级预防措施，加强优生优育宣传，提高孕前产前检查，以减少出生缺陷的发生与出生，提高人口素质。
目的：瞭解柳州市齣生缺陷髮生的變化趨勢及流行病學特徵，為開展齣生缺陷病因研究及製訂齣生缺陷綜閤榦預措施提供參攷依據。方法對2009～2013年柳州市範圍內119傢助產醫院的圍產兒齣生缺陷鑑測資料進行統計分析。結果5年共鑑測圍產兒239343例，髮現齣生缺陷兒4324例，齣生缺陷總髮生率為18．07‰，整體呈現上升趨勢（χ2趨勢＝44．393，P＜0．001）。齣生缺陷髮生率前5位順位依次是先天性心髒病、多指／趾、外耳其他畸形、總脣裂、馬蹄內翻足。缺陷髮生率城鎮（22．36‰）高于農村（14．94‰，（χ2＝194．909，P＜0．001）；男性（20．34‰）高于女性（15．33‰）（χ2＝84．584，P＜0．001）。結論柳州市齣生缺陷髮生率處于較高水平，應有針對性的進一步加大齣生缺陷的一、二級預防措施，加彊優生優育宣傳，提高孕前產前檢查，以減少齣生缺陷的髮生與齣生，提高人口素質。
목적：료해류주시출생결함발생적변화추세급류행병학특정，위개전출생결함병인연구급제정출생결함종합간예조시제공삼고의거。방법대2009～2013년류주시범위내119가조산의원적위산인출생결함감측자료진행통계분석。결과5년공감측위산인239343례，발현출생결함인4324례，출생결함총발생솔위18．07‰，정체정현상승추세（χ2추세＝44．393，P＜0．001）。출생결함발생솔전5위순위의차시선천성심장병、다지／지、외이기타기형、총진렬、마제내번족。결함발생솔성진（22．36‰）고우농촌（14．94‰，（χ2＝194．909，P＜0．001）；남성（20．34‰）고우녀성（15．33‰）（χ2＝84．584，P＜0．001）。결론류주시출생결함발생솔처우교고수평，응유침대성적진일보가대출생결함적일、이급예방조시，가강우생우육선전，제고잉전산전검사，이감소출생결함적발생여출생，제고인구소질。
Objective To analyze the variation and epidemiologic features of birth defects in Liuzhou City , so as to provide basis for analyzing etiology of birth defects and making interventional measures .Methods SPSS 13.0 software was used for statistical analysis of monitoring data of birth defects in 119 obstetric hospitals in Liuzhou city from 2009 to 2013.Results Totally 4 324 infants with birth defects were found among 239 343 perinatal infants, and the incidence was 18.07‰with an increasing trend ( χtrend2 =44.393, P<0.001).The top five in the sequence of birth defects was congenital heart disease , multiple fingers/toes, other outer ear deformities , total cleft lip and horseshoe varus foot.Incidence of birth defects in town (22.36‰) was higher than in countryside (14.94 ‰) (χ2 =194.909,P<0.001), and that of the male (20.34‰) was higher than the female (15.33‰) (χ2 =84.584,P<0.001).Conclusion The incidence of birth defects maintains relatively high level in Liuzhou City .Therefore, some targeted measures to strengthen primary and secondary prevention , enhance propaganda on healthy birth and child development , and increase antenatal check should be taken to reduce the incidence of birth defects and improve the quality of birth population .
