中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
6期
989-990,1024
,共3页
子痫前期%胎盘早剥%危险因素%单因素分析%Logistic回归分析
子癇前期%胎盤早剝%危險因素%單因素分析%Logistic迴歸分析
자간전기%태반조박%위험인소%단인소분석%Logistic회귀분석
preeclampsia ( PE)%placental abruption ( PA)%risk factors%univariate analysis%Logistic regression anlaysis
目的：对子痫前期（ PE）患者胎盘早剥（ PA）的相关危险因素进行分析，以期为预防此类患者的胎盘早剥提供依据。方法选择2010年6月至2013年9月在宝鸡市金台医院产科分娩的PE产妇268例，其中48例合并PA作为观察组，而另外220例未合并PA的患者作为对照组。回顾性分析两组患者的病例资料，对相关因素进行单因素分析及多因素Logistic回归分析。结果单因素分析结果显示，观察组孕周、纤维蛋白原（FIB）和血清白蛋白（ALB）显著低于对照组（t值分别2．059、3．591、8．200，均P＜0．05），而舒张压（DBP）、尿素氮、肌酐、24h尿蛋白（24h UP）显著高于对照组（t值分别2．652、4．583、6．852、3．632，均P＜0．05），观察组患者分娩史显著低于对照组（χ2＝8．731，P＜0．05）。多因素Logistic回归分析结果显示，FIB、24hUP、ALB、肌酐和分娩史是PE合并PA的独立危险因素（OR值分别为1．369、1．198、1．205、1．283、1．231，均P＜0．05）。结论 PE患者发生PA的病理机制复杂，与FIB、24hUP、ALB、肌酐和分娩史有关，临床工作中应尽早发现PA发生的高危因素，采取有效措施进行预防。
目的：對子癇前期（ PE）患者胎盤早剝（ PA）的相關危險因素進行分析，以期為預防此類患者的胎盤早剝提供依據。方法選擇2010年6月至2013年9月在寶鷄市金檯醫院產科分娩的PE產婦268例，其中48例閤併PA作為觀察組，而另外220例未閤併PA的患者作為對照組。迴顧性分析兩組患者的病例資料，對相關因素進行單因素分析及多因素Logistic迴歸分析。結果單因素分析結果顯示，觀察組孕週、纖維蛋白原（FIB）和血清白蛋白（ALB）顯著低于對照組（t值分彆2．059、3．591、8．200，均P＜0．05），而舒張壓（DBP）、尿素氮、肌酐、24h尿蛋白（24h UP）顯著高于對照組（t值分彆2．652、4．583、6．852、3．632，均P＜0．05），觀察組患者分娩史顯著低于對照組（χ2＝8．731，P＜0．05）。多因素Logistic迴歸分析結果顯示，FIB、24hUP、ALB、肌酐和分娩史是PE閤併PA的獨立危險因素（OR值分彆為1．369、1．198、1．205、1．283、1．231，均P＜0．05）。結論 PE患者髮生PA的病理機製複雜，與FIB、24hUP、ALB、肌酐和分娩史有關，臨床工作中應儘早髮現PA髮生的高危因素，採取有效措施進行預防。
목적：대자간전기（ PE）환자태반조박（ PA）적상관위험인소진행분석，이기위예방차류환자적태반조박제공의거。방법선택2010년6월지2013년9월재보계시금태의원산과분면적PE산부268례，기중48례합병PA작위관찰조，이령외220례미합병PA적환자작위대조조。회고성분석량조환자적병례자료，대상관인소진행단인소분석급다인소Logistic회귀분석。결과단인소분석결과현시，관찰조잉주、섬유단백원（FIB）화혈청백단백（ALB）현저저우대조조（t치분별2．059、3．591、8．200，균P＜0．05），이서장압（DBP）、뇨소담、기항、24h뇨단백（24h UP）현저고우대조조（t치분별2．652、4．583、6．852、3．632，균P＜0．05），관찰조환자분면사현저저우대조조（χ2＝8．731，P＜0．05）。다인소Logistic회귀분석결과현시，FIB、24hUP、ALB、기항화분면사시PE합병PA적독립위험인소（OR치분별위1．369、1．198、1．205、1．283、1．231，균P＜0．05）。결론 PE환자발생PA적병리궤제복잡，여FIB、24hUP、ALB、기항화분면사유관，림상공작중응진조발현PA발생적고위인소，채취유효조시진행예방。
Objective To analyze the risk factors of placental abruption (PA) in patients with preeclampsia (PE), so as to provide reference for the prevention of the disease .Methods From June 2010 to September 2013 268 cases with PE delivering in the maternity department of Jintai Hospital of Baoji City in Shaanxi Province were selected , including 48 cases combining PA in observation group and the other 220 cases not combining PA in control group .Clinical data of two groups were retrospectively analyzed , and the factors were analyzed with univariate analysis and multivariate Logistic regression analysis .Results Univariate analysis showed that the gestational age , fibrinogen (FIB) and serum albumin (ALB) in the observation group were significantly decreased than those in the control group (t value was 2.059, 3.591 and 8.200, respectively, all P<0.05), but diastolic pressure (DBP), blood urea nitrogen (BUN), creatinine (Cr) and 24h urine protein (24h UP) were significantly increased (t value was 2.652, 4.583, 6.852 and 3.632, respectively, all P<0.05).The childbirth history in the observation group was significantly lower than that in the control group (χ2 =8.731,P<0.05).Multivariate Logistic regression analysis showed that FIB , 24h UP, ALB, Cr and childbirth history were the independent risk factors for PE combining PA (OR value was 1.369, 1.198, 1.205, 1.283 and 1.231, respectively, all P<0.05).Conclusion The pathological mechanism of PA combining PE is complex, and it is related with FIB, 24h UP, ALB, Cr and childbirth history.The high-risk factors of PA should be found as early as possible in clinics , and effective measures should be taken to prevent the occurrence of PA .
