中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2014年
12期
59-62
,共4页
夏舟岚%李忠香%马英英%陆月红%陈惠娟
夏舟嵐%李忠香%馬英英%陸月紅%陳惠娟
하주람%리충향%마영영%륙월홍%진혜연
宫腔内人工授精%射精障碍%逆行射精%不射精
宮腔內人工授精%射精障礙%逆行射精%不射精
궁강내인공수정%사정장애%역행사정%불사정
Intrauterine insemination%Ejaculatory disorder%Retrograde ejaculation%Aneaculation
目的:探讨对男性射精障碍所致不育夫妻进行宫腔内人工授精(Intrauterine insemination, IUI)的临床疗效。方法:对14例男性射精障碍所致不育夫妻进行宫腔内人工授精的临床资料进行回顾性分析,其中2例为逆行射精,12例为不射精。逆行射精者,取精前常规口服碳酸氢钠碱化尿液,排尿后手淫取精,收集标本;对于不射精者,常规手淫取精收集标本。采用密度梯度离心法处理精液,随后进行IUI。根据IUI精液处理后精子前向运动总数(Processed total motile sperm count,PTMS),将IUI周期分为三组:PTMS<10×106(A组)、PTMS<10×106~20×106(B组)和PTMS≥20×106(C组),统计每组的妊娠率,并对妊娠周期与非妊娠周期处理后注入宫腔内精液参数进行统计学分析。结果:14例男性射精障碍的不育夫妻经30个周期IUI治疗,10例女方怀孕,临床周期妊娠率为33.33%,临床累积妊娠率为71.43%。PTMS<10×106(A组)、10×106~20×106(B 组)和≥20×106(C 组),这三组周期妊娠率分别25.00%、40.00%和33.33%。妊娠周期与非妊娠周期处理后注入宫腔内精液参数均无统计学差异(P均>0.05)。结论:对男性射精障碍所致不孕夫妻进行IUI治疗,效果明显、临床实用性强。
目的:探討對男性射精障礙所緻不育伕妻進行宮腔內人工授精(Intrauterine insemination, IUI)的臨床療效。方法:對14例男性射精障礙所緻不育伕妻進行宮腔內人工授精的臨床資料進行迴顧性分析,其中2例為逆行射精,12例為不射精。逆行射精者,取精前常規口服碳痠氫鈉堿化尿液,排尿後手淫取精,收集標本;對于不射精者,常規手淫取精收集標本。採用密度梯度離心法處理精液,隨後進行IUI。根據IUI精液處理後精子前嚮運動總數(Processed total motile sperm count,PTMS),將IUI週期分為三組:PTMS<10×106(A組)、PTMS<10×106~20×106(B組)和PTMS≥20×106(C組),統計每組的妊娠率,併對妊娠週期與非妊娠週期處理後註入宮腔內精液參數進行統計學分析。結果:14例男性射精障礙的不育伕妻經30箇週期IUI治療,10例女方懷孕,臨床週期妊娠率為33.33%,臨床纍積妊娠率為71.43%。PTMS<10×106(A組)、10×106~20×106(B 組)和≥20×106(C 組),這三組週期妊娠率分彆25.00%、40.00%和33.33%。妊娠週期與非妊娠週期處理後註入宮腔內精液參數均無統計學差異(P均>0.05)。結論:對男性射精障礙所緻不孕伕妻進行IUI治療,效果明顯、臨床實用性彊。
목적:탐토대남성사정장애소치불육부처진행궁강내인공수정(Intrauterine insemination, IUI)적림상료효。방법:대14례남성사정장애소치불육부처진행궁강내인공수정적림상자료진행회고성분석,기중2례위역행사정,12례위불사정。역행사정자,취정전상규구복탄산경납감화뇨액,배뇨후수음취정,수집표본;대우불사정자,상규수음취정수집표본。채용밀도제도리심법처리정액,수후진행IUI。근거IUI정액처리후정자전향운동총수(Processed total motile sperm count,PTMS),장IUI주기분위삼조:PTMS<10×106(A조)、PTMS<10×106~20×106(B조)화PTMS≥20×106(C조),통계매조적임신솔,병대임신주기여비임신주기처리후주입궁강내정액삼수진행통계학분석。결과:14례남성사정장애적불육부처경30개주기IUI치료,10례녀방부잉,림상주기임신솔위33.33%,림상루적임신솔위71.43%。PTMS<10×106(A조)、10×106~20×106(B 조)화≥20×106(C 조),저삼조주기임신솔분별25.00%、40.00%화33.33%。임신주기여비임신주기처리후주입궁강내정액삼수균무통계학차이(P균>0.05)。결론:대남성사정장애소치불잉부처진행IUI치료,효과명현、림상실용성강。
Objectives:To investigate the Intrauterine insemination,IUI clinical outcome of infertility couples with male ejaculation disorders.Methods:The clinical data of 14 male infertility couples with ejaculation disorders,who received intrauterine insemination,was analyzed retrospectively,including 2 cases of retrograde ejaculation and 12 cases of anejaculation.For patients with retrograde ejaculation,before sperm retrieval,they took the sodium bicarbonate alka-line urine orally.After urination masturbation,the sperm was collected;for patients with anejaculation,masturbation was used for sperm collection.IUI was conducted after density gradient centrifugation of the sperm.According to the pro-cessed total motile sperm count,the IUI cycle was divided into three groups:PTMS<10 ×106 (group A),<10 ×106 ~20 ×106 (group B)and ≥20 ×106 (group C),the pregnancy rate of each group was calculate and the intrauterine semen parameters between pregnant cycle and non-pregnant cycle were statistically analyzed.Results:After 30 cycles of IUI therapy,in 14 couples with male ejaculation obstacle infertility,10 cases got pregnancy;clinical cycle pregnancy rate was 33.33%,and clinical cumulative pregnancy rate was 71.43%.Conclusion:The treatment of IUI for infertile couples caused by male ejaculation disorders is obviously effective with clinical practicability.