中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
12期
1481-1484
,共4页
高血压%骨质疏松骨折%β受体阻滞剂%骨密度
高血壓%骨質疏鬆骨摺%β受體阻滯劑%骨密度
고혈압%골질소송골절%β수체조체제%골밀도
Hypertension%Osteoporotic fracture%β-Adrenergic receptor blocker%Bone mineral density
高血压和骨质疏松是与年龄相关的老年人群常见共发病，两者具有一定的共同病因。高血压能够使患者的骨密度降低，从而增加患者骨质疏松性骨折的风险，β受体阻滞剂是高血压治疗常用药物之一。近年来研究表明β受体阻滞剂能够提高老年高血压患者的骨密度，从而降低老年高血压患者骨质疏松性骨折发病风险。本文从骨质疏松和骨质疏松性骨折流行病学、高血压增加骨质疏松骨折风险及β受体阻滞剂通过影响骨代谢降低骨质疏松骨折风险等方面作一综述。
高血壓和骨質疏鬆是與年齡相關的老年人群常見共髮病，兩者具有一定的共同病因。高血壓能夠使患者的骨密度降低，從而增加患者骨質疏鬆性骨摺的風險，β受體阻滯劑是高血壓治療常用藥物之一。近年來研究錶明β受體阻滯劑能夠提高老年高血壓患者的骨密度，從而降低老年高血壓患者骨質疏鬆性骨摺髮病風險。本文從骨質疏鬆和骨質疏鬆性骨摺流行病學、高血壓增加骨質疏鬆骨摺風險及β受體阻滯劑通過影響骨代謝降低骨質疏鬆骨摺風險等方麵作一綜述。
고혈압화골질소송시여년령상관적노년인군상견공발병，량자구유일정적공동병인。고혈압능구사환자적골밀도강저，종이증가환자골질소송성골절적풍험，β수체조체제시고혈압치료상용약물지일。근년래연구표명β수체조체제능구제고노년고혈압환자적골밀도，종이강저노년고혈압환자골질소송성골절발병풍험。본문종골질소송화골질소송성골절류행병학、고혈압증가골질소송골절풍험급β수체조체제통과영향골대사강저골질소송골절풍험등방면작일종술。
Hypertension and osteoporosis are of high incidence and often coexist in the aging population that shares a similar etiopathology.High blood pressure can reduce the bone mineral density (BMD) in hypertension patients, resulting in increase of the osteoporotic fracture risk.β-Adrenergic receptor blocker ( BB) is one of the most used drugs to treat hypertension.Recent studies indicate that BB can improve BMD in hypertension patient, therefore reduce the risk of osteoporotic fracture.This article reviews the factors that influence the risk of osteoporotic fracture from epidemiology of osteoporosis and osteoporotic fracture, high blood pressure, and bone metabolic change due to BB in hypertension patients.
