CAJ | 학술논문

目的：观察围绝经妇女激素替代治疗（HRT）后生命质量的变化。方法：选择围绝经有明显症状和不同程度心理症状的病人80例，采取HRT 进行治疗，疗程为3个月，选用WHO生存质量测定量表简表（WHOQOL－BREF）评价治疗前后各项指标的变化，并做统计学处理。结果：所有患者治疗3个月后，生理、心理、环境各项指标均较治疗前显著改善，差异有统计学意义（P＜0.01），但社会功能方面并无明显的改善（P ＞0.5），总分明显改善，差异有统计学意义（P ＜0.001）。结论：短期HRT 能安全、有效改善围绝经期妇女生理、心理相关症状，明显提高生活质量，患者依从性高。
목적：관찰위절경부녀격소체대치료（HRT）후생명질량적변화。방법：선택위절경유명현증상화불동정도심리증상적병인80례，채취HRT 진행치료，료정위3개월，선용WHO생존질량측정량표간표（WHOQOL－BREF）평개치료전후각항지표적변화，병주통계학처리。결과：소유환자치료3개월후，생리、심리、배경각항지표균교치료전현저개선，차이유통계학의의（P＜0.01），단사회공능방면병무명현적개선（P ＞0.5），총분명현개선，차이유통계학의의（P ＜0.001）。결론：단기HRT 능안전、유효개선위절경기부녀생리、심리상관증상，명현제고생활질량，환자의종성고。
Objectives:To observe the changes in the life quality of postmenopausal women after hormone replacement therapy.Methods:80 objects with obvious peri menopausal symptoms and significantly different levels of psychological symptoms were selected and treated with hormone replacement therapy for 3 months.Their life qual-ity before and after the treatment was surveyed with WHOQOL-BREF,and changes in each indicator was statisti-cally analyzed and compared.Results:After treatment,all the physiological,psychological,environmental indica-tors had been improved greatly,with statistically significant difference (P<0.01),but the social function had not been improved significantly (P>0.5 ),while total score improved significantly,with statistical difference (P<0.01).Conclusion:Short-term HRT can effectively improve the physiological and psychological symptoms of per-imenopausal women,and improve their life quality,with high patients’compliance.