CAJ | 학술논문

目的：通过测量长、短期精密度和短期准确度对双能X线吸收法（ dual－energy X－ray absorptiometry ，DXA）骨密度仪进行质量控制。方法①长期精密度：对质量保证（Quality Assurance，QA）模块连续1年的测试数据进行统计分析，分别计算其高、中、低骨密度、均值骨密度、骨矿盐含量、投影面积的变异系数（ coefficient of variation ，CV）；②短期精密度：取连续25天的QA模块测试数据，计算高、中、低骨密度平均值和标准差（standard deviation，SD），制作Shewhart质控图。另外选取30名志愿者，分别测量L1－4椎体，双侧股骨颈、大粗隆、Ward＇s三角、全髋关节的骨密度（bone mineral density，BMD）值，计算均方根变异系数（ root mean square of the CV ，RMS－CV）；③短期准确度：取连续25天的QA模块测试数据，计算高、中、低骨密度的准确度。结果①长期精密度：QA模块测量高、中、低骨密度、均值骨密度、骨矿盐含量、投影面积的CV分别为0．37％、0．37％、0．41％、0．43％、0．47％、0．12％；②短期精密度：连续25天QA模块测试数据均符合Shewhart 法则；30例受试者L1－4椎体，双侧股骨颈、大粗隆、Ward＇s 三角、全髋关节各测量部位的RMS－CV 分别为1．3％、0．8％、0．9％、1．2％、1．3％、1．5％、1．6％、0．6％、0．6％；③短期准确度：连续25天QA模块测试数据的高、中、低骨密度的准确度分别为－0．07％、0．10％、0．60％。结论进行长、短期精密度和准确度测试能反映双能X线吸收骨密度仪的一致性和可靠性，可有效提高骨质疏松的流行病学研究、诊断、治疗、药物试验研究的可信度。
목적：통과측량장、단기정밀도화단기준학도대쌍능X선흡수법（ dual－energy X－ray absorptiometry ，DXA）골밀도의진행질량공제。방법①장기정밀도：대질량보증（Quality Assurance，QA）모괴련속1년적측시수거진행통계분석，분별계산기고、중、저골밀도、균치골밀도、골광염함량、투영면적적변이계수（ coefficient of variation ，CV）；②단기정밀도：취련속25천적QA모괴측시수거，계산고、중、저골밀도평균치화표준차（standard deviation，SD），제작Shewhart질공도。령외선취30명지원자，분별측량L1－4추체，쌍측고골경、대조륭、Ward＇s삼각、전관관절적골밀도（bone mineral density，BMD）치，계산균방근변이계수（ root mean square of the CV ，RMS－CV）；③단기준학도：취련속25천적QA모괴측시수거，계산고、중、저골밀도적준학도。결과①장기정밀도：QA모괴측량고、중、저골밀도、균치골밀도、골광염함량、투영면적적CV분별위0．37％、0．37％、0．41％、0．43％、0．47％、0．12％；②단기정밀도：련속25천QA모괴측시수거균부합Shewhart 법칙；30례수시자L1－4추체，쌍측고골경、대조륭、Ward＇s 삼각、전관관절각측량부위적RMS－CV 분별위1．3％、0．8％、0．9％、1．2％、1．3％、1．5％、1．6％、0．6％、0．6％；③단기준학도：련속25천QA모괴측시수거적고、중、저골밀도적준학도분별위－0．07％、0．10％、0．60％。결론진행장、단기정밀도화준학도측시능반영쌍능X선흡수골밀도의적일치성화가고성，가유효제고골질소송적류행병학연구、진단、치료、약물시험연구적가신도。
Objective To study the long-term and short-term precision and short-term accuracy of quality assurance ( QA) in using dual-energy X-ray absorptiometry ( DXA ) .Methods 1 ) Long-term precision: the consecutive 1-year data from QA phantom were statistical analyzed, and the high-, middle-, and low-bone mineral density ( BMD ) , mean BMD, bone mineral content, and projected area of coefficient of variation (CV) were calculated.2)Short-term precision:the data of QA phantom of 25 consecutive days were collected.The mean and standard deviation ( SD) of the high-, middle-, and low-BMD were calculated. The Shewhart chart was created.BMD of the L1-4 vertebral body, bilateral femoral neck, the greater trochanter, ward triangle, and the total hip joint of 30 volunteers was measured.The root mean square of the CV (RMS-CV) was calculated.3) Short-term accuracy:the data of QA phantom of 25 consecutive days were collected.The accuracy of the high-, middle-, and low-BMD were calculated.Results 1) Long-term precision:the CV of high-, middle-, low-BMD, mean BMD, bone mineral content, and projected area was 0.37%, 0.37%, 0.41%, 0.43%, 0.47%, and 0.12%, respectively.2) Short-term precision:the data of QA phantom for 25 consecutive days met the Shewhart rule.The RMS-CV value of L1-4 vertebral body, the bilateral femoral neck, the the bilateral greater trochanter, the the bilateral Ward triangle, and the total hip joint of 30 volunteers was 1.3%, 0.8%, 0.9%, 1.2%, 1.3%, 1.5%, 1.6%, 0.6%, and 0.6%, respectively.3) Short-term accuracy:the accuracy of the data of high-, middle -, low-BMD yielded by scanning QA phantom for 25 consecutive days was -0.07%, 0.10%, and 0.60%, respectively.Conclusion The consistency and reliability of DXA can be reflected by the long-term and short-term precision and accuracy trail.It can effectively raise the credibility of the epidemiological investigation, diagnosis, treatment, and drug testing of osteoporosis.