实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2014年
12期
1661-1663
,共3页
仲几春%徐娟%薛玉保
仲幾春%徐娟%薛玉保
중궤춘%서연%설옥보
长春瑞滨%顺铂%蒽环类%紫杉类%耐药%乳腺癌
長春瑞濱%順鉑%蒽環類%紫杉類%耐藥%乳腺癌
장춘서빈%순박%은배류%자삼류%내약%유선암
Vinorelbine(NVB)%Cisplatin(DDP)%Anthracycline%Taxane%Drug resistance%Breast cancer
目的：探讨长春瑞滨联合顺铂方案治疗蒽环及紫杉类耐药晚期乳腺癌的疗效。方法将60例蒽环及紫杉类耐药的晚期乳腺癌患者随机分为观察组（30例）和对照组（30例）。观察组采用长春瑞滨联合顺铂方案治疗，对照组采取经典CAF治疗方案。结果治疗有效率观察组为60．00％，对照组为30．00％，观察组疗效显著优于对照组；不良反应的发生率2组之间没有明显差异。结论长春瑞滨联合顺铂治疗蒽环及紫杉类耐药的晚期乳腺癌，具有很好的疗效和较低的毒副作用。
目的：探討長春瑞濱聯閤順鉑方案治療蒽環及紫杉類耐藥晚期乳腺癌的療效。方法將60例蒽環及紫杉類耐藥的晚期乳腺癌患者隨機分為觀察組（30例）和對照組（30例）。觀察組採用長春瑞濱聯閤順鉑方案治療，對照組採取經典CAF治療方案。結果治療有效率觀察組為60．00％，對照組為30．00％，觀察組療效顯著優于對照組；不良反應的髮生率2組之間沒有明顯差異。結論長春瑞濱聯閤順鉑治療蒽環及紫杉類耐藥的晚期乳腺癌，具有很好的療效和較低的毒副作用。
목적：탐토장춘서빈연합순박방안치료은배급자삼류내약만기유선암적료효。방법장60례은배급자삼류내약적만기유선암환자수궤분위관찰조（30례）화대조조（30례）。관찰조채용장춘서빈연합순박방안치료，대조조채취경전CAF치료방안。결과치료유효솔관찰조위60．00％，대조조위30．00％，관찰조료효현저우우대조조；불량반응적발생솔2조지간몰유명현차이。결론장춘서빈연합순박치료은배급자삼류내약적만기유선암，구유흔호적료효화교저적독부작용。
Objective To analyzes the efficacy of NVB plus DDP in the treatment of anthracycline and taxane -resistant advanced breast cancer .Methods 60 cases of advanced breast cancer resistant to anthracycline and taxane were randomly divid -ed into the observation group(30 cases)and the control group.The observation group received NVB plus DDP treatment ,and the control group received classic CAF treatment .Results The effective rate of the observation group and the control group were 60.00%and 30.00%.The curative effect of the control group was significantly better than that of the control group ;there had no difference in the incidence of adverse reactions between the 2 groups.Conclusion NVB plus DDP in the treatment of anthracy-cline and taxane-resistant advanced breast cancer has good efficacy and low toxicities .
