CAJ | 학술논문

幽门螺杆菌（Hp）是一种寄生于胃黏膜的致病菌，既往大量研究已经证实Hp能够通过多种机制引发慢性胃炎及消化性溃疡。在Hp与消化系统的其他常见疾病关系的研究中表明，Hp是胃癌、原发性肝癌、大肠癌、功能性胃肠病的致病因素；可能是炎症性肠病的保护因素；对于食管癌及胃食管反流病，Hp与其之间的关系尚不确定，存在不同的观点。该文就Hp与以上消化系统疾病之间的关系进行流行病学及发病机制等方面予以综述，以便临床上更系统的治疗消化系统疾病。
유문라간균（Hp）시일충기생우위점막적치병균，기왕대량연구이경증실Hp능구통과다충궤제인발만성위염급소화성궤양。재Hp여소화계통적기타상견질병관계적연구중표명，Hp시위암、원발성간암、대장암、공능성위장병적치병인소；가능시염증성장병적보호인소；대우식관암급위식관반류병，Hp여기지간적관계상불학정，존재불동적관점。해문취Hp여이상소화계통질병지간적관계진행류행병학급발병궤제등방면여이종술，이편림상상경계통적치료소화계통질병。
Helicobacter pylori(Hp) is a pathogen parasitizing in the gastric mucosa,a large number of studies have confirmed that Hp can cause chronic gastritis and peptic ulcer through a variety of mechanisms . It is indicated in the studies of the relationships between Hp and other digestive system diseases that Hp is a risk factor of gastric cancer,primary hepatocellular carcinoma,colorectal cancer and functional gastrointestinal disorders,and it may be a protective factor in inflammatory bowel disease ,while its correlation with esophage-al carcinoma and gastroesophageal reflux disease still remains uncertain and controversial .Here is to make a review of the relationship between Hp and digestive system diseases from the aspects of epidemiology and pathogenesis,in order to seek more systematic clinical treatment method for digestive system diseases .