CAJ | 학술논문

镁离子的血管活性作用受到广泛重视。目前研究表明，镁离子可以通过内皮依赖性和内皮非依赖性血管舒缩系统调节血管舒缩，镁离子也可通过体液调节系统发挥作用。镁离子在人体内的重要作用包括抗心律失常、调节血管紧张度、调节血管收缩性、调节葡萄糖代谢、维持体内胰岛素稳态。此外，低镁血症与氧化应激、促炎性状态、内皮功能紊乱、血小板聚集、胰岛素抵抗、高血糖症有关。截至目前，各类研究数据显示体内血镁水平与高血压病呈现相反的关系。
미리자적혈관활성작용수도엄범중시。목전연구표명，미리자가이통과내피의뢰성화내피비의뢰성혈관서축계통조절혈관서축，미리자야가통과체액조절계통발휘작용。미리자재인체내적중요작용포괄항심률실상、조절혈관긴장도、조절혈관수축성、조절포도당대사、유지체내이도소은태。차외，저미혈증여양화응격、촉염성상태、내피공능문란、혈소판취집、이도소저항、고혈당증유관。절지목전，각류연구수거현시체내혈미수평여고혈압병정현상반적관계。
The vasoactive effect of magnesium has drawn wide attention .The present studies show that magnesium regulates vascular smooth muscle contraction and relaxation by endothelium-dependent and endo-thelium-independent vasomotor system.Magnesium also plays a role in body fluid regulation system .The important functions of magnesium in the body include antiarrhythmic effect ,actions in vascular tone,contrac-tility,glucose metabolism,and insulin homeostasis.In addition,lower concentrations of magnesium are associ-ated with oxidative stress,proinflammatory state,endothelial dysfunction,platelet aggregation,insulin resist-ance,and hyperglycemia.Up to now,various studies indicate that there is an inverse correlation between ser-um magnesium and hypertension in vivo.