CAJ | 학술논문

近年来，脉冲电磁场（ PEMFs）在分子、细胞、组织和器官水平对成骨的影响已被广泛研究。PEMFs通过影响细胞分子信号转导、调节相关基因、蛋白合成以及各种细胞因子分泌来调节细胞增殖和分化，抑制骨吸收，促进新骨形成和骨折愈合，并被广泛用于临床上治疗骨折、骨折延迟愈合、骨不连以及脊柱融合。此外，PEMFs还能够提高与组织工程支架联合培养的种子细胞活性。
근년래，맥충전자장（ PEMFs）재분자、세포、조직화기관수평대성골적영향이피엄범연구。PEMFs통과영향세포분자신호전도、조절상관기인、단백합성이급각충세포인자분비래조절세포증식화분화，억제골흡수，촉진신골형성화골절유합，병피엄범용우림상상치료골절、골절연지유합、골불련이급척주융합。차외，PEMFs환능구제고여조직공정지가연합배양적충자세포활성。
In recent years,pulsed electromagnetic fields(PEMFs) has been studied extensively in osteo-genic effect at the molecular,cellular,tissue and organ levels.Here is to make a review of the effects of PEMFs on bone formation and bone resorption were reviewed.By regulating cellular,molecular signal transduc-tion,related gene expression,protein synthesis and secretion of various cytokines,PEMFs regulate cell prolifera-tion and differentiation,inhibit bone resorption,promote new bone formation and bone fracture healing ,and is widely used in the clinical treatment for bone fractures ,delayed union,nonunion,and spinal fusion.In addition, PEMFs can also improve the activities of seed cells co -cultured with tissue engineering scaffolds .