医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2014年
24期
4522-4524
,共3页
韦晓(综述)%尹瑞兴(审校)
韋曉(綜述)%尹瑞興(審校)
위효(종술)%윤서흥(심교)
非ST段抬高型急性冠状动脉综合征%不稳定型心绞痛%抗栓治疗
非ST段抬高型急性冠狀動脈綜閤徵%不穩定型心絞痛%抗栓治療
비ST단태고형급성관상동맥종합정%불은정형심교통%항전치료
Non-ST-segment elevation acute coronary syndromes%Unstable angina pectoris%An-tithrombotic treatment
非ST段抬高急性冠状动脉综合征的治疗包括药物治疗、经皮腔内冠状动脉介入治疗和冠状动脉旁路移植术，而抗栓药物治疗大大减少了患者的病死率、心肌梗死发生率及致残率，同时提高患者生活质量。抗栓药物包括抗血小板和抗凝药。其中抗血小板药有阿司匹林、磷酸腺苷受体拮抗剂和血小板膜糖蛋白抗体拮抗剂等；抗凝药有普通肝素和低分子肝素、抗Ⅹa因子抑制药和直接凝血酶抑制剂等。
非ST段抬高急性冠狀動脈綜閤徵的治療包括藥物治療、經皮腔內冠狀動脈介入治療和冠狀動脈徬路移植術，而抗栓藥物治療大大減少瞭患者的病死率、心肌梗死髮生率及緻殘率，同時提高患者生活質量。抗栓藥物包括抗血小闆和抗凝藥。其中抗血小闆藥有阿司匹林、燐痠腺苷受體拮抗劑和血小闆膜糖蛋白抗體拮抗劑等；抗凝藥有普通肝素和低分子肝素、抗Ⅹa因子抑製藥和直接凝血酶抑製劑等。
비ST단태고급성관상동맥종합정적치료포괄약물치료、경피강내관상동맥개입치료화관상동맥방로이식술，이항전약물치료대대감소료환자적병사솔、심기경사발생솔급치잔솔，동시제고환자생활질량。항전약물포괄항혈소판화항응약。기중항혈소판약유아사필림、린산선감수체길항제화혈소판막당단백항체길항제등；항응약유보통간소화저분자간소、항Ⅹa인자억제약화직접응혈매억제제등。
The treatment of non-ST-segment elevation acute coronary syndromes includes medical treat-ment,percutaneous coronary intervention and coronary artery bypass grafting,and antithrombotic therapy sig-nificantly reduces mortality in patients and the incidence of myocardial infarction and disability rate,and im-proving the quality of life of patients. There are two kinds of antithrombotic drugs,antiplatelet and anticoagu-lant drugs. The antiplatelet agents include aspirin,adenosine monophosphate receptor antagonist and platelet membrane glycoprotein antibody antagonist. The anticoagulant drugs consist of heparin,low molecular weight heparin,anti factor Ⅹa inhibitors and the direct thrombin inhibitor etc.
