CAJ | 학술논문

目的：观察氨溴特罗联合低分子肝素钙对慢性阻塞性肺疾病急性加重期（AECOPD）患者的治疗效果。方法将126例AECOPD患者随机分为观察组和对照组，每组各63例。两组均进行常规综合治疗，观察组加用氨溴特罗及低分子肝素钙，治疗周期均为7d，对两组患者治疗前后PaCO2、PaO2、SaO2等血气分析指标及DD、FIB等凝血指标进行比较。结果治疗后，两组患者PaCO2、PaO2、SaO2等血气分析指标及DD、FIB等凝血指标均较治疗前有明显改善（P<0.05），且观察组患者上述指标改善程度显著优于对照组（P<0.05）。结论氨溴特罗联合低分子肝素钙治疗AECOPD的疗效确切，可明显改善AECOPD患者PaCO2、PaO2、SaO2等血气分析指标及DD、FIB等凝血指标。
목적：관찰안추특라연합저분자간소개대만성조새성폐질병급성가중기（AECOPD）환자적치료효과。방법장126례AECOPD환자수궤분위관찰조화대조조，매조각63례。량조균진행상규종합치료，관찰조가용안추특라급저분자간소개，치료주기균위7d，대량조환자치료전후PaCO2、PaO2、SaO2등혈기분석지표급DD、FIB등응혈지표진행비교。결과치료후，량조환자PaCO2、PaO2、SaO2등혈기분석지표급DD、FIB등응혈지표균교치료전유명현개선（P<0.05），차관찰조환자상술지표개선정도현저우우대조조（P<0.05）。결론안추특라연합저분자간소개치료AECOPD적료효학절，가명현개선AECOPD환자PaCO2、PaO2、SaO2등혈기분석지표급DD、FIB등응혈지표。
Objective?To?observe?the?clinical?effects?of?Ambrocol?combined?with?low?molecular?weight?heparin?calcium?on?acute?exacerbation?of?chronic?obstructive?pulmonary?disease?(AECOPD)?patients.?Methods??126?patients?with?AECOPD?were?randomly?divided?into?observation?group?and?control?group,?63?cases?in?each?group.?The?patients?of?two?groups?received?routine?treatment,?patients?of?the?observation?group?plus?Ambrocol?and?low?molecular?weight?heparin,?the?treatment?cycle?were?7?d,?before?and?after?treatment,?the?indexes?such?as?PaCO2,?PaO2,?SaO2, DD, FIB were analyzed and compared.Results??After?treatment,?the?indexes?such?as?PaCO2,?PaO2,?SaO2, DD, FIB were signiifcantly improved compared with before treatment in two groups (P<0.05),?and?the?indexes?in?the?observation?group?improved signiifcantly better than those in the control group (P<0.05).?Conclusion??The?effect?of?Ambrocol?combined?with?low?molecular?heparin?calcium?in?the?treatment?of?AECOPD?is?accurate,?the?method?can?obviously?improve?the?indexes?such?as?PaCO2,?PaO2,?SaO2,?DD,?FIB?of?patients?with?AECOPD.