CAJ | 학술논문

目的：探讨冰水漱口对乳腺癌化疗患者口腔溃疡的预防作用。方法2012年6月至2013年12月期间我院收治的乳腺癌化疗患者258例，随机分为短时冰水漱口组83例；持续冰水漱口组67例；空白对照组108例。研究3组患者口腔溃疡发生率及构成情况。结果短时冰水漱口组及持续冰水漱口组患者较空白对照组患者口腔溃疡发生率低，差异均有统计学意义（P<0.05）；短时冰水漱口组与持续冰水漱口组口腔溃疡发生率无明显差异（P>0.05）。结论乳腺癌患者化疗药物输注当天冰水漱口可有效预防化疗所致口腔溃疡，经济、有效、患者依从性高，值得在临床推广应用。
목적：탐토빙수수구대유선암화료환자구강궤양적예방작용。방법2012년6월지2013년12월기간아원수치적유선암화료환자258례，수궤분위단시빙수수구조83례；지속빙수수구조67례；공백대조조108례。연구3조환자구강궤양발생솔급구성정황。결과단시빙수수구조급지속빙수수구조환자교공백대조조환자구강궤양발생솔저，차이균유통계학의의（P<0.05）；단시빙수수구조여지속빙수수구조구강궤양발생솔무명현차이（P>0.05）。결론유선암환자화료약물수주당천빙수수구가유효예방화료소치구강궤양，경제、유효、환자의종성고，치득재림상추엄응용。
Objective?To?investigate?the?effect?of?ice?water?gargling?on?prevention?of?oral?ulcer?reduced?by?chemotherapy?in?breast?cancer?patients.?Methods?258?cases?of?breast?cancer?patients?undergoing?chemotherapy?in?our?hospital?during?the?period?from?June?2012?to?December?2013?,?were?randomly?divided?into?short-term?ice?water?gargling?group?83?cases;?continuous?ice?water?gargling?group?67?cases;?blank?control?group,?108?cases.?Research?the?incidence?and?composition?of?oral?ulcer?on?three?groups?of?patients.?Results?Short-term?ice??water?gargling?group?and?continuous?ice??water?gargling?group?have a lower incidence of oral ulcer than control group, the differences were statistically signiifcant(P<0.05);?Between?short-term?and?continuous?water?gargling group, there was no signiifcant difference in the incidence of oral ulcer(P>0.05).?Conclusion?Breast?cancer?patients?using?ice?water?gargling?during?the?day?infusing?chemotherapy?drugs?can?effectively?prevent?the?incidence?of?oral?ulcer,?this?methods?has?advantage?of?economical,?effective,?and?high?patient?compliance,?it?is?worth?popularizing?in?clinical.