中国药物经济学
中國藥物經濟學
중국약물경제학
CHINA JOURNAL OF PHARMACEUTICAL ECONOMICS
2014年
z1期
53-54,55
,共3页
翼状胬肉%翼状胬肉切除术%角膜缘干细胞移植术%泪液分泌试验%泪膜破裂时间
翼狀胬肉%翼狀胬肉切除術%角膜緣榦細胞移植術%淚液分泌試驗%淚膜破裂時間
익상노육%익상노육절제술%각막연간세포이식술%루액분비시험%루막파렬시간
Pterygium%Pterygium excision%Limbal stem cel transplantation%Schirmer I test%BUT
目的：探讨翼状胬肉切除联合角膜缘干细胞移植术对眼表功能的影响。方法选取无并发症的原发性翼状胬肉患者146例（146只眼），施行翼状胬肉切除联合角膜缘干细胞移植术，所有患者术后均随访1个月。分别于术前1天及术后1个月行术眼泪液分泌试验（Schirmer I test）及泪膜破裂时间（BUT）检查并比较。结果患者术眼Schirmer I试验术前为（7.51±1.62）mm/5min，BUT术前为（8.91±1.65）s，均低于正常。而在施行翼状胬肉切除联合角膜缘干细胞移植术后，患者术眼Schirmer I试验术后1个月为（11.71±2.88）mm/5min，BUT术后1个月为（10.59±1.71）s，均较术前明显延长，差异有统计学意义（P＜0.01）。结论翼状胬肉可对眼表功能造成了明显损害，而翼状胬肉切除联合角膜缘干细胞移植术可提高泪膜的稳定性，改善眼表功能，是治疗翼状胬肉的一种安全有效的手术方式。
目的：探討翼狀胬肉切除聯閤角膜緣榦細胞移植術對眼錶功能的影響。方法選取無併髮癥的原髮性翼狀胬肉患者146例（146隻眼），施行翼狀胬肉切除聯閤角膜緣榦細胞移植術，所有患者術後均隨訪1箇月。分彆于術前1天及術後1箇月行術眼淚液分泌試驗（Schirmer I test）及淚膜破裂時間（BUT）檢查併比較。結果患者術眼Schirmer I試驗術前為（7.51±1.62）mm/5min，BUT術前為（8.91±1.65）s，均低于正常。而在施行翼狀胬肉切除聯閤角膜緣榦細胞移植術後，患者術眼Schirmer I試驗術後1箇月為（11.71±2.88）mm/5min，BUT術後1箇月為（10.59±1.71）s，均較術前明顯延長，差異有統計學意義（P＜0.01）。結論翼狀胬肉可對眼錶功能造成瞭明顯損害，而翼狀胬肉切除聯閤角膜緣榦細胞移植術可提高淚膜的穩定性，改善眼錶功能，是治療翼狀胬肉的一種安全有效的手術方式。
목적：탐토익상노육절제연합각막연간세포이식술대안표공능적영향。방법선취무병발증적원발성익상노육환자146례（146지안），시행익상노육절제연합각막연간세포이식술，소유환자술후균수방1개월。분별우술전1천급술후1개월행술안루액분비시험（Schirmer I test）급루막파렬시간（BUT）검사병비교。결과환자술안Schirmer I시험술전위（7.51±1.62）mm/5min，BUT술전위（8.91±1.65）s，균저우정상。이재시행익상노육절제연합각막연간세포이식술후，환자술안Schirmer I시험술후1개월위（11.71±2.88）mm/5min，BUT술후1개월위（10.59±1.71）s，균교술전명현연장，차이유통계학의의（P＜0.01）。결론익상노육가대안표공능조성료명현손해，이익상노육절제연합각막연간세포이식술가제고루막적은정성，개선안표공능，시치료익상노육적일충안전유효적수술방식。
Objective To observation the effect of ocular surface function after pterygium excision combined with limbal stem cel transplantation.Methods 146 eyes of 146 pterygium patients without complications were undergone pterygium excision combined with limbal stem cel transplantation. Al patients were folowed-up for 1 months.Schirmer I test and BUT were recorded and compared between preoperative and postoperative 1 months.Results The Schirmer I test of preoperative was (7.51±1.62) mm/5min, the BUT of preoperative was (8.91±1.65) s, it was lower than normal. But after pterygium excision combined with limbal stem cel transplantation, The Schirmer I test of postoperative 1 months was(11.71±2.88)mm/5min,the BUT of postoperative 1 months was(10.59±1.71)s,it was significantly longer than preoperative(P<0.01).Conclusion Ocular surface function is damaged significantly by pterygium.Pterygium excision combined with limbal stem cel transplantation as one of the security and effective methods,it is abled to improve the stability of the tear film and ocular surface function.
