CAJ | 학술논문

目的：对唑来膦酸单药治疗肺癌骨转移患者的疗效及不良反应进行分析。方法对我院40例肺癌骨转移患者进行临床研究，随机分为对照组和研究组，对对照组使用注射用帕米膦酸治疗，对研究组使用注射用唑来膦酸治疗，比较两组的疗效及不良反应。结果两组患者疼痛缓解情况差异不明显（P＞0.05）；研究组和对照组患者不良反应总发生率分别为15%和10%，不存在统计学上的意义（P＞0.05）。结论使用唑来膦酸对肺癌骨转移患者进行治疗后患者的疼痛得到有效缓解，且不良反应较少。
목적：대서래련산단약치료폐암골전이환자적료효급불량반응진행분석。방법대아원40례폐암골전이환자진행림상연구，수궤분위대조조화연구조，대대조조사용주사용파미련산치료，대연구조사용주사용서래련산치료，비교량조적료효급불량반응。결과량조환자동통완해정황차이불명현（P＞0.05）；연구조화대조조환자불량반응총발생솔분별위15%화10%，불존재통계학상적의의（P＞0.05）。결론사용서래련산대폐암골전이환자진행치료후환자적동통득도유효완해，차불량반응교소。
ObjectiveTo discuss azole phosphonic acid monotherapy to treat lung cancer patients with bone metastases and it curative effect and adverse reactions.MethodsThe clinical studies of lung cancer patients with bone metastases in 40 cases, they were randomly divided into control group and the team, to the control group using para meters phosphonic acid for injection treatment, the team used injection with azole phosphonic acid treatment, compared two groups of curative effect and adverse reactions. ResultsTwo groups of patients with pain relief situation is not obvious difference (P>0.05), observation group and control group in incidence of adverse reactions in patients with a total of 15% and 10% respectively, there was no statistical significance (P>0.05).ConclusionUsing azole phosphonic acid treatment in patients with bone metastases of lung cancer patients after is effective in pain relief, and has less adverse reaction.