CAJ | 학술논문

目的：分析某院血液内科住院患者抗感染药物应用情况，为血液病经验性抗感染治疗提供参考。方法采用回顾性分析方法，随机抽取247份血液内科出院患者病例，分析病原菌分布、经验性抗感染治疗及抗菌药物应用情况。结果血液内科住院患者中发热患者占27．1％，中性粒细胞减少患者占25．5％，行经验性抗感染治疗患者占91．3％；感染以革兰阴性菌为主，真菌感染率较高；抗感染治疗以头孢菌素类、喹诺酮类及抗真菌药物应用最多。结论血液病患者易发生院内感染，经验性抗感染治疗对疾病的控制非常重要，同时亦应加强细菌培养并根据药敏结果选择最佳治疗方案。
목적：분석모원혈액내과주원환자항감염약물응용정황，위혈액병경험성항감염치료제공삼고。방법채용회고성분석방법，수궤추취247빈혈액내과출원환자병례，분석병원균분포、경험성항감염치료급항균약물응용정황。결과혈액내과주원환자중발열환자점27．1％，중성립세포감소환자점25．5％，행경험성항감염치료환자점91．3％；감염이혁란음성균위주，진균감염솔교고；항감염치료이두포균소류、규낙동류급항진균약물응용최다。결론혈액병환자역발생원내감염，경험성항감염치료대질병적공제비상중요，동시역응가강세균배양병근거약민결과선택최가치료방안。
Objective To investigate the antibacterial application in hematologic diseases treatmens ,and provide reference to empiric anti‐infective therapy .Methods A retrospective analysis was performed and 247 discharged patients of hematology diseases were randomly selected .The pathogen distribution ,empiric anti‐infective therapy and antibacterial drugs application were analyzed . Results Hematology fever patients accounted for 27 .1% ,neutropenic patients accounted for 25 .5% ,and empiric anti‐infective therapy patients accounted for 91 .3% .Main patients infected by G - bacterial and fungal infections rate was high .The antibacte‐rial drugs were mainly cephalosporin ,quinolones and antifungal .Conclusion Patients with blood diseases were prone to have nos‐ocomial infections and empiric anti‐infective therapy was very important .We should strengthen the bacterial culture work and se‐lect the optimal treatment regimen based on susceptibility results .