CAJ | 학술논문

多糖是生物体内广泛存在且具有多种生物活性的一类天然大分子物质，其对机体免疫系统具有重要调节作用。研究表明，植物多糖可通过与免疫细胞表面的多种受体结合、激活不同的信号通路来调控动物机体的免疫系统，包括：刺激巨噬细胞、T/B淋巴细胞、自然杀伤细胞的分泌或增殖；调节细胞因子的释放；促进抗体的分泌；激活补体系统等。本文主要对植物多糖对动物机体的免疫调节作用及其分子作用机制相关研究进行综述。
다당시생물체내엄범존재차구유다충생물활성적일류천연대분자물질，기대궤체면역계통구유중요조절작용。연구표명，식물다당가통과여면역세포표면적다충수체결합、격활불동적신호통로래조공동물궤체적면역계통，포괄：자격거서세포、T/B림파세포、자연살상세포적분비혹증식；조절세포인자적석방；촉진항체적분비；격활보체계통등。본문주요대식물다당대동물궤체적면역조절작용급기분자작용궤제상관연구진행종술。
Polysaccharides, a kind of natural macromolecule, is widespread occurrence in biological bodies and has many kinds of biological activities, which plays an important role in regulating immune system. Previous studies documented that phytogenic polysaccharides could regulate animals ’ immune system by combining to membrane receptors of immune cells and initiating the special signaling pathways. This included stimulating the secretion or proliferation of macrophages, T/B lymphocytes and natural killer ( NK) cells, modulating the re-lease of cytokines, promoting the production of antibodies, and activating the complement system, etc. This paper mainly reviews the immune regulation roles of phytogenic polysaccharides and related molecular mecha-nisms.