山东师范大学学报（自然科学版）
山東師範大學學報（自然科學版）
산동사범대학학보（자연과학판）
JOURNAL OF SHANGOND NORMAL UNIVERSITY(NATURAL SCIENCE)
2015年
1期
83-86
,共4页
邻苯二甲酸酯%高效液相色谱%配方乳粉
鄰苯二甲痠酯%高效液相色譜%配方乳粉
린분이갑산지%고효액상색보%배방유분
phthalate esters%high performance liquid chromatography%powdered formulas
本文建立了可用于婴幼儿配方乳粉中13种邻苯二甲酸酯类环境激素测定的超高效液相色谱－二极管阵列紫外检测器分析方法．样品经甲醇饱和正己烷超声提取、柱分离富集与净化后，以乙腈和水为流动相进行梯度洗脱．所检测的13种邻苯二甲酸酯的线性范围为0．5－50 mg／L，检测下限在0．05－0．4 mg／L之间，加标回收率为92－102％，相对标准偏差均小于10％，该方法操作简便、分析时间短、灵敏度高，适用于婴幼儿配方乳粉中邻苯二甲酸酯的筛查分析．
本文建立瞭可用于嬰幼兒配方乳粉中13種鄰苯二甲痠酯類環境激素測定的超高效液相色譜－二極管陣列紫外檢測器分析方法．樣品經甲醇飽和正己烷超聲提取、柱分離富集與淨化後，以乙腈和水為流動相進行梯度洗脫．所檢測的13種鄰苯二甲痠酯的線性範圍為0．5－50 mg／L，檢測下限在0．05－0．4 mg／L之間，加標迴收率為92－102％，相對標準偏差均小于10％，該方法操作簡便、分析時間短、靈敏度高，適用于嬰幼兒配方乳粉中鄰苯二甲痠酯的篩查分析．
본문건립료가용우영유인배방유분중13충린분이갑산지류배경격소측정적초고효액상색보－이겁관진렬자외검측기분석방법．양품경갑순포화정기완초성제취、주분리부집여정화후，이을정화수위류동상진행제도세탈．소검측적13충린분이갑산지적선성범위위0．5－50 mg／L，검측하한재0．05－0．4 mg／L지간，가표회수솔위92－102％，상대표준편차균소우10％，해방법조작간편、분석시간단、령민도고，괄용우영유인배방유분중린분이갑산지적사사분석．
A method was developed for the simultaneous determination of thirteen phthalate esters in powderedformulas for infants and young children by ultra performance liquid chromatography -photo -diode array.Sampleswere extracted with methanol saturated by n -hexane in an ultrasonic field, cleaned up by refrigeratedcentrifugation,and then the supernatant was cleaned by 0.2 μm hydrophobic membranes.The target analytes wereseparated on an HSST3 column with gradient elution using acetonitrile and water as mobile phases.Theidentification and quantification were achieved by using photo -diode array detector.Linear ranges of thirteenphthalate esters were from 0.5 to 50 mg /L.Limits of detection were in the range of 0.05 -0.4 mg/L.Theaverage recoveries of the method were from 92% to 102%.The relative standard deviations were less than 10%.The method is simple,sensitive and rapid.It is suitable for the simultaneous determination of thirteen phthalateesters in powdered formulas for infants and young children.
