CAJ | 학술논문

报道1例紫杉醇脂质体化疗致重度出血性膀胱炎患者的病例资料并进行文献复习。1例宫颈癌术后放化疗后复发患者，接受紫杉醇脂质体270 mg和顺铂联合静脉化疗，化疗后第3天出现IV度出血性膀胱炎，入院后给予留置尿管及膀胱冲洗、碳酸氢钠静脉注射碱化尿液、抗感染、止血、输血、积极抗休克处理及输尿管镜下膀胱积血清除，患者最终死亡。在紫杉醇脂质体化疗过程中，需要警惕发生出血性膀胱炎。
보도1례자삼순지질체화료치중도출혈성방광염환자적병례자료병진행문헌복습。1례궁경암술후방화료후복발환자，접수자삼순지질체270 mg화순박연합정맥화료，화료후제3천출현IV도출혈성방광염，입원후급여류치뇨관급방광충세、탄산경납정맥주사감화뇨액、항감염、지혈、수혈、적겁항휴극처리급수뇨관경하방광적혈청제，환자최종사망。재자삼순지질체화료과정중，수요경척발생출혈성방광염。
The clinical data of one case of hemorrhagic cystitis caused by chemotherapy of paclitaxel liposome was re-ported. One patient with recurrent cervical cancer after chemoradiatherapy and operation received paclitaxel liposome 270 mg and chemotherapy with cisplatin combined with intravenous. IV degree of hemorrhagic cystitis occurred on the 3rd day after chemotherapy. The patient then received indwelling urinary catheter, bladder irrigation, alkalization of urine by intra-venous injection with sodium bicarbonate, anti-infection, hemostasis, blood transfusion, positive antishock and ureteroscopic clearance of hematocyst, but still died at last. We should be alert to the occurrence of hemorrhagic cystitis in the process of paclitaxel liposome chemotherapy.