浙江临床医学
浙江臨床醫學
절강림상의학
ZHEJIANG CLINICAL MEDICAL JOURNAL
2014年
12期
1876-1877
,共2页
血清%血清爱帕琳肽%脂联素%游离脂肪酸%基质金属蛋白酶%充血性心力衰竭
血清%血清愛帕琳肽%脂聯素%遊離脂肪痠%基質金屬蛋白酶%充血性心力衰竭
혈청%혈청애파림태%지련소%유리지방산%기질금속단백매%충혈성심력쇠갈
Serum%Apelin%APN%FFA%MMP%Congestive heart failure
目的：探讨血清爱帕琳肽（Apelin）、脂联素（APN），游离脂肪酸（FFA）及基质金属蛋白酶（MMP）与充血性心力衰竭的关系。方法本资料中80例充血性心力衰竭患者设为观察组，同期的80名健康者为对照组，将两组的血清Apelin、APN、FFA及MMP水平进行检测及比较，然后将观察组中不同分级及分类患者的血清Apelin、APN、FFA及MMP水平进行分别统计及比较，并以Logistic分析处理上述血清项目与充血性心力衰竭的关系。结果观察组的血清Apelin、APN、FFA及MMP水平均高于对照组，且观察组中分级较高者高于分级较低者，收缩性心力衰竭患者则高于舒张性心力衰竭患者，经Logistic分析显示上述血清检测指标与充血性心力衰竭有密切的关系（P均<0.05）。结论充血性心力衰竭患者的血清Apelin、APN、FFA及MMP呈现明显升高的状态，上述血清指标均与充血性心力衰竭有密切的关系。
目的：探討血清愛帕琳肽（Apelin）、脂聯素（APN），遊離脂肪痠（FFA）及基質金屬蛋白酶（MMP）與充血性心力衰竭的關繫。方法本資料中80例充血性心力衰竭患者設為觀察組，同期的80名健康者為對照組，將兩組的血清Apelin、APN、FFA及MMP水平進行檢測及比較，然後將觀察組中不同分級及分類患者的血清Apelin、APN、FFA及MMP水平進行分彆統計及比較，併以Logistic分析處理上述血清項目與充血性心力衰竭的關繫。結果觀察組的血清Apelin、APN、FFA及MMP水平均高于對照組，且觀察組中分級較高者高于分級較低者，收縮性心力衰竭患者則高于舒張性心力衰竭患者，經Logistic分析顯示上述血清檢測指標與充血性心力衰竭有密切的關繫（P均<0.05）。結論充血性心力衰竭患者的血清Apelin、APN、FFA及MMP呈現明顯升高的狀態，上述血清指標均與充血性心力衰竭有密切的關繫。
목적：탐토혈청애파림태（Apelin）、지련소（APN），유리지방산（FFA）급기질금속단백매（MMP）여충혈성심력쇠갈적관계。방법본자료중80례충혈성심력쇠갈환자설위관찰조，동기적80명건강자위대조조，장량조적혈청Apelin、APN、FFA급MMP수평진행검측급비교，연후장관찰조중불동분급급분류환자적혈청Apelin、APN、FFA급MMP수평진행분별통계급비교，병이Logistic분석처리상술혈청항목여충혈성심력쇠갈적관계。결과관찰조적혈청Apelin、APN、FFA급MMP수평균고우대조조，차관찰조중분급교고자고우분급교저자，수축성심력쇠갈환자칙고우서장성심력쇠갈환자，경Logistic분석현시상술혈청검측지표여충혈성심력쇠갈유밀절적관계（P균<0.05）。결론충혈성심력쇠갈환자적혈청Apelin、APN、FFA급MMP정현명현승고적상태，상술혈청지표균여충혈성심력쇠갈유밀절적관계。
ObjectiveTo investigate the relationship between the serum Apelin,APN,FFA,MMP and congestive heart failure.Methods80 patients with congestive heart failure in our hospital from July 2012 to March 2014 were selected as observation group,80 healthy persons with health examination at the same time were the control group,then the serum Apelin,APN,FFA and MMP of two groups were detected and compared,then the serum Apelin,APN,FFA and MMP of observation group with different grades and classification were respectively analyzed and compared,then relationship between those serum items and congestive heart failure were analyzed by the logistic analysis.ResultsThe serum Apelin,APN,FFA and MMP of observation group were all higher than those of control group,those of observation group with higher grades were all higher than those of patients with lower grades, those of patients with systolic heart failure were all higher than those of patients with diastolic heart failure,and those serum indexes all had close relationship to the congestive heart failure by the Logistic analysis,allP<0.05.ConclusionThe serum Apelin,APN, FFA and MMP of patients with congestive heart failure show obvious higher state,and those serum indexes have close relationship to the congestive heart failure.
