实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
PRACTICAL JOURNAL OF CARDIAC CEREBRAL PNEUMAL AND VASCULAR DISEASE
2014年
12期
95-96
,共2页
高血压,妊娠性%硝苯地平%治疗结果
高血壓,妊娠性%硝苯地平%治療結果
고혈압,임신성%초분지평%치료결과
Hypertension,pregnancy - induced%Nifedipine%Treatment outcome
目的：观察硝苯地平不同用药方案治疗妊娠高血压综合征的临床疗效。方法选取2011年3月—2014年3月上栗县妇幼保健院收治的妊娠高血压综合征患者118例，按照不同用药方案分为长效组61例和短效组57例。长效组患者口服硝苯地平缓释片治疗，短效组患者口服短效硝苯地平片治疗，均连续服用7 d 为1个疗程。比较两组患者治疗2个疗程后临床疗效、分娩方式及妊娠结局，并观察治疗期间不良反应发生情况。结果治疗2个疗程后，长效组总有效率为95.1％，高于短效组的82.5％（P ＜0.05）。长效组患者剖宫产率（18.0％）低于短效组（35.1％）、胎儿窘迫发生率（8.2％）低于短效组（21.1％）（P ＜0.05）；两组患者不良反应发生率（8.2％比10.5％）比较，差异无统计学意义（P ＞0.05）。结论长效硝苯地平治疗妊娠高血压综合征在降压、降低剖宫产率及改善妊娠结局方面优于短效硝苯地平。
目的：觀察硝苯地平不同用藥方案治療妊娠高血壓綜閤徵的臨床療效。方法選取2011年3月—2014年3月上慄縣婦幼保健院收治的妊娠高血壓綜閤徵患者118例，按照不同用藥方案分為長效組61例和短效組57例。長效組患者口服硝苯地平緩釋片治療，短效組患者口服短效硝苯地平片治療，均連續服用7 d 為1箇療程。比較兩組患者治療2箇療程後臨床療效、分娩方式及妊娠結跼，併觀察治療期間不良反應髮生情況。結果治療2箇療程後，長效組總有效率為95.1％，高于短效組的82.5％（P ＜0.05）。長效組患者剖宮產率（18.0％）低于短效組（35.1％）、胎兒窘迫髮生率（8.2％）低于短效組（21.1％）（P ＜0.05）；兩組患者不良反應髮生率（8.2％比10.5％）比較，差異無統計學意義（P ＞0.05）。結論長效硝苯地平治療妊娠高血壓綜閤徵在降壓、降低剖宮產率及改善妊娠結跼方麵優于短效硝苯地平。
목적：관찰초분지평불동용약방안치료임신고혈압종합정적림상료효。방법선취2011년3월—2014년3월상률현부유보건원수치적임신고혈압종합정환자118례，안조불동용약방안분위장효조61례화단효조57례。장효조환자구복초분지평완석편치료，단효조환자구복단효초분지평편치료，균련속복용7 d 위1개료정。비교량조환자치료2개료정후림상료효、분면방식급임신결국，병관찰치료기간불량반응발생정황。결과치료2개료정후，장효조총유효솔위95.1％，고우단효조적82.5％（P ＜0.05）。장효조환자부궁산솔（18.0％）저우단효조（35.1％）、태인군박발생솔（8.2％）저우단효조（21.1％）（P ＜0.05）；량조환자불량반응발생솔（8.2％비10.5％）비교，차이무통계학의의（P ＞0.05）。결론장효초분지평치료임신고혈압종합정재강압、강저부궁산솔급개선임신결국방면우우단효초분지평。
Objective To observe the curative effect of different drug programs of nifedipine on pregnancy - induced hypertension. Methods A total of 118 patients with pregnancy - induced hypertension were selected in the Maternal and Child Health Hospital of Shangli County from March 2011 to March 2014,and they were divided into groups A(n ﹦ 61)and B(n ﹦57)according to drug programs of nifedipine. A group given oral extended release nifedipine tablets,B group given short - acting nifedipine tablets,both groups treated for 7 days as a course of treatment. After 2 courses of treatment,curative effect,delivery mode,pregnancy outcome were compared between the two groups,and incidence of adverse reactions during treatment was ob- served. Results After 2 courses of treatment,the total effective rate of A group was 95. 1% ,was higher than that of B group of 82. 5% (P < 0. 05). The cesarean delivery rate of A group was 18. 0% ,was lower than that of control group of 35. 1% (P <0. 05);the incidence of fetal distress of A group was 8. 2% ,was lower than that of control group of 21. 1% (P < 0. 05). The incidence of adverse reactions of A group was 8. 2% ,that of B group was 10. 5% ,the difference was not significantly different (P > 0. 05). Conclusion Extended release nifedipine tablets has better curative effect in reducing blood pressure,cesarean de- livery rate and improving pregnancy outcome than short - acting nifedipine tablets in treating patients with pregnancy - induced hy- pertension.
