实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
PRACTICAL JOURNAL OF CARDIAC CEREBRAL PNEUMAL AND VASCULAR DISEASE
2014年
12期
61-62
,共2页
肺肿瘤%癌胚抗原%磷酸丙酮酸水合酶%角蛋白 19
肺腫瘤%癌胚抗原%燐痠丙酮痠水閤酶%角蛋白 19
폐종류%암배항원%린산병동산수합매%각단백 19
Lung neoplasms%Carcinoembryonic antigen%Phosphopyruvate hydratase%Keratin - 19
目的：观察肺癌患者血清癌胚抗原（CEA）、神经元特异性烯醇化酶（NSE）、细胞角蛋白21-1（CY- FRA21-1）水平变化，探讨其临床意义。方法选取海安县肿瘤医院2012—2013年收治的经病理检查确诊的肺癌患者35例为肺癌组，肺部良性疾病患者38例为良性病变组，同期50例体检健康者为对照组，检测其血清 CEA、NSE、CYFRA21-1水平。结果肺癌组患者血清 CEA、NSE、CYFRA21-1水平均高于良性病变组、对照组（P ＜0.05）；良性病变组与对照组受试者血清 CEA、NSE、CYFRA21-1水平比较，差异均无统计学意义（P ＞0.05）。35例肺癌患者治疗后血清 CEA、NSE、CYFRA21-1水平均低于治疗前（P ＜0.05）。结论肺癌患者血清 CEA、NSE、CYFRA21-1水平明显升高，血清 CEA、NSE、CYFRA21-1水平检测可用于肺癌治疗疗效判断及预后评估。
目的：觀察肺癌患者血清癌胚抗原（CEA）、神經元特異性烯醇化酶（NSE）、細胞角蛋白21-1（CY- FRA21-1）水平變化，探討其臨床意義。方法選取海安縣腫瘤醫院2012—2013年收治的經病理檢查確診的肺癌患者35例為肺癌組，肺部良性疾病患者38例為良性病變組，同期50例體檢健康者為對照組，檢測其血清 CEA、NSE、CYFRA21-1水平。結果肺癌組患者血清 CEA、NSE、CYFRA21-1水平均高于良性病變組、對照組（P ＜0.05）；良性病變組與對照組受試者血清 CEA、NSE、CYFRA21-1水平比較，差異均無統計學意義（P ＞0.05）。35例肺癌患者治療後血清 CEA、NSE、CYFRA21-1水平均低于治療前（P ＜0.05）。結論肺癌患者血清 CEA、NSE、CYFRA21-1水平明顯升高，血清 CEA、NSE、CYFRA21-1水平檢測可用于肺癌治療療效判斷及預後評估。
목적：관찰폐암환자혈청암배항원（CEA）、신경원특이성희순화매（NSE）、세포각단백21-1（CY- FRA21-1）수평변화，탐토기림상의의。방법선취해안현종류의원2012—2013년수치적경병리검사학진적폐암환자35례위폐암조，폐부량성질병환자38례위량성병변조，동기50례체검건강자위대조조，검측기혈청 CEA、NSE、CYFRA21-1수평。결과폐암조환자혈청 CEA、NSE、CYFRA21-1수평균고우량성병변조、대조조（P ＜0.05）；량성병변조여대조조수시자혈청 CEA、NSE、CYFRA21-1수평비교，차이균무통계학의의（P ＞0.05）。35례폐암환자치료후혈청 CEA、NSE、CYFRA21-1수평균저우치료전（P ＜0.05）。결론폐암환자혈청 CEA、NSE、CYFRA21-1수평명현승고，혈청 CEA、NSE、CYFRA21-1수평검측가용우폐암치료료효판단급예후평고。
Objective To observe the serum levels of CEA,NSE and CYFRA21 - 1 of patients with lung cancer,to investigate its clinical significance. Methods From 2012 to 2013 in the Cancer Hospital of Haian County,35 patients with lung cancer diagnosed by pathological examination were selected as A group,38 patients with benign lung disease were selected as B group,50 healthy cases were selected as C group. Serum levels of CEA,NSE and CYFRA21 - 1 of the three groups were detec- ted. Results Serum levels of CEA,NSE and CYFRA21 - 1 of A group were higher than those of B group and C group(P <0. 05),but no significant differences was found of serum levels of CEA,NSE and CYFRA21 - 1 between B group and C group. Serum levels of CEA,NSE and CYFRA21 - 1 of A group were reduced after treatment(P < 0. 05). Conclusion Serum levels of CEA,NSE and CYFRA21 - 1 of patients with are significantly higher,can be used in judging the clinical effect and e- valuating the prognosis.
