实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
PRACTICAL JOURNAL OF CARDIAC CEREBRAL PNEUMAL AND VASCULAR DISEASE
2014年
12期
43-44
,共2页
高血压%老年人%氯沙坦钾氢氯噻嗪片%治疗结果
高血壓%老年人%氯沙坦鉀氫氯噻嗪片%治療結果
고혈압%노년인%록사탄갑경록새진편%치료결과
Hypertension%Aged%Losartan potassium and hydrochlorothiazide tablets%Treatment outcome
目的：观察氯沙坦钾氢氯噻嗪片治疗老年原发性高血压的临床疗效。方法选择2010年3月—2013年3月在河池市金城江区南桥社区卫生服务中心进行治疗的老年原发性高血压患者110例，随机分为治疗组和对照组，各55例。治疗组患者给予氯沙坦钾氢氯噻嗪片治疗，对照组给予氯沙坦钾片治疗，两组患者均治疗2个月。比较两组患者治疗前后收缩压（SBP）、舒张压（DBP）及心率（HR）；观察两组患者临床疗效及治疗期间不良反应发生情况。结果治疗组患者总有效率为96.4％，高于对照组的83.6％（P ＜0.05）。治疗前两组患者 DBP、SBP 及 HR 比较，差异无统计学意义（P ＞0.05）。治疗后治疗组患者 DBP 和 SBP 低于对照组（P ＜0.05）；两组患者治疗后 HR 比较，差异无统计学意义（P ＞0.05）。观察组患者不良反应发生率为5.5％，与对照组的7.2％比较，差异无统计学意义（P ＞0.05）。结论氯沙坦钾氢氯噻嗪片治疗老年原发性高血压的临床疗效确切，且安全性较高。
目的：觀察氯沙坦鉀氫氯噻嗪片治療老年原髮性高血壓的臨床療效。方法選擇2010年3月—2013年3月在河池市金城江區南橋社區衛生服務中心進行治療的老年原髮性高血壓患者110例，隨機分為治療組和對照組，各55例。治療組患者給予氯沙坦鉀氫氯噻嗪片治療，對照組給予氯沙坦鉀片治療，兩組患者均治療2箇月。比較兩組患者治療前後收縮壓（SBP）、舒張壓（DBP）及心率（HR）；觀察兩組患者臨床療效及治療期間不良反應髮生情況。結果治療組患者總有效率為96.4％，高于對照組的83.6％（P ＜0.05）。治療前兩組患者 DBP、SBP 及 HR 比較，差異無統計學意義（P ＞0.05）。治療後治療組患者 DBP 和 SBP 低于對照組（P ＜0.05）；兩組患者治療後 HR 比較，差異無統計學意義（P ＞0.05）。觀察組患者不良反應髮生率為5.5％，與對照組的7.2％比較，差異無統計學意義（P ＞0.05）。結論氯沙坦鉀氫氯噻嗪片治療老年原髮性高血壓的臨床療效確切，且安全性較高。
목적：관찰록사탄갑경록새진편치료노년원발성고혈압적림상료효。방법선택2010년3월—2013년3월재하지시금성강구남교사구위생복무중심진행치료적노년원발성고혈압환자110례，수궤분위치료조화대조조，각55례。치료조환자급여록사탄갑경록새진편치료，대조조급여록사탄갑편치료，량조환자균치료2개월。비교량조환자치료전후수축압（SBP）、서장압（DBP）급심솔（HR）；관찰량조환자림상료효급치료기간불량반응발생정황。결과치료조환자총유효솔위96.4％，고우대조조적83.6％（P ＜0.05）。치료전량조환자 DBP、SBP 급 HR 비교，차이무통계학의의（P ＞0.05）。치료후치료조환자 DBP 화 SBP 저우대조조（P ＜0.05）；량조환자치료후 HR 비교，차이무통계학의의（P ＞0.05）。관찰조환자불량반응발생솔위5.5％，여대조조적7.2％비교，차이무통계학의의（P ＞0.05）。결론록사탄갑경록새진편치료노년원발성고혈압적림상료효학절，차안전성교고。
Objective To observe the clinical effect of losartan potassium and hydrochlorothiazide tablets in treating elderly patients with primary hypertension. Methods From March 2010 to March 2013,a total of 110 elderly patients with pri- mary hypertension were selected in the Nanqiao Community Health Service Center,Jinchengjiang District,Hechi,and they were randomly divided into control group and treatment group,each of 55 cases. Control group given losartan potassium tablets,treat- ment group given losartan potassium and hydrochlorothiazide tablets;both groups treated for 2 months. Systolic blood pressure, diastolic blood pressure,heart rate between the two groups were compared before and after treatment,and clinical effect,inci- dence of adverse reactions during treatment were observed. Results The total effective rate of treatment group was 96. 4% ,was higher than that of control group of 83. 6% (P < 0. 05). There was no significant differences of systolic blood pressure,diastolic blood pressure and heart rate between the two groups before treatment(P > 0. 05). Systolic blood pressure,diastolic blood pres- sure of treatment group were lower than those of control group after treatment(P < 0. 05);but there was no significant differences of heart rate between the two groups after treatment( P > 0. 05). The incidence of adverse reactions of treatment group was 5. 5% ,that of control group was 7. 2% ,the difference was not significantly different(P > 0. 05). Conclusion Losartan po- tassium and hydrochlorothiazide tablets has certain clinical effect in treating elderly patients with primary hypertension,and is safe.
