CAJ | 학술논문

目的探讨全身化疗配合 CT 定位椎旁抽脓及局部注药治疗脊柱结核的疗效。方法回顾性分析1290例脊柱结核的临床资料，所有患者采用全身抗结核治疗18个月，结合 CT定位椎旁抽脓及局部注药治疗时间(55±14)d；其中310例患者有脊柱手术指征，在全身抗结核治疗结合CT定位椎旁抽脓及局部注药治疗2~4周后行病灶清除术。结果980例脊柱结核患者未发生交叉感染及窦道形成，随访3~5年，均达到治愈及停药标准，另310例手术后达到治愈。结论全身化疗配合CT定位椎旁抽脓及局部注药治疗结合全身抗结核治疗，对不伴有严重脊髓损伤或严重脊柱后凸畸形的脊柱结核疗效满意，值得临床推广。
목적탐토전신화료배합 CT 정위추방추농급국부주약치료척주결핵적료효。방법회고성분석1290례척주결핵적림상자료，소유환자채용전신항결핵치료18개월，결합 CT정위추방추농급국부주약치료시간(55±14)d；기중310례환자유척주수술지정，재전신항결핵치료결합CT정위추방추농급국부주약치료2~4주후행병조청제술。결과980례척주결핵환자미발생교차감염급두도형성，수방3~5년，균체도치유급정약표준，령310례수술후체도치유。결론전신화료배합CT정위추방추농급국부주약치료결합전신항결핵치료，대불반유엄중척수손상혹엄중척주후철기형적척주결핵료효만의，치득림상추엄。
Obj ective]To explore the efficacy of CT-guided para-vertebral aspiration and local drug inj ection for the treatment of spinal tuberculosis.[Methods]Clinical data of 1290 patients with spinal tuberculosis were an-alyzed retrospectively.Among them,980 patients received systemic anti-tuberculosis therapy for 18 months and CT-guided para-vertebral aspiration and local drug injection for 55±14 days,while 310 patients received systemic anti-tuberculosis therapy,CT-guided para-vertebral aspiration and local drug inj ection for 2~4 weeks,and then underwent spinal debridement.[Results]No cross infection and sinus formation were found in 980 patients.The patients were followed up for 3~5 years and met the curative and drug withdrawal criteria.After surgery,310 pa-tients were cured.[Conclusion]CT-guided para-vertebral aspiration and local drug inj ection combined with system-ic anti-tuberculosis therapy for the treatment of spinal tuberculosis without severe spinal inj ury or serious kyphosis has satisfactory effect.Therefore,it is worthy of clinical promotion.