CAJ | 학술논문

目的：探讨呼出气一氧化氮(FeNO)测定哮喘患者气道炎性反应的临床价值。方法：2013年2月-2014年5月收治哮喘患者167例作为A组，并将其分为A1组(哮喘控制组)、A2组(部分控制组)与A3组(未控制组)。选择同期50例健康人员作为 B 组。对 A、B 两组患者的 FeNO 进行测定，对比两组 FEV1%、FEV1/FVC%的差异。结果：A 组患者FEV1%、FEV1/FVC%低于B组，差异有统计学意义(P＜0.05)。A组FeNO高于B组，差异有统计学意义(P＜0.05)。治疗后，A1组与A2组患者FeNO值均显著的下降，但 A2组 FeNO 与 A3组、A1组比较，差异无统计学意义(P＞0.05)。结论：FeNO水平能够对哮喘患者气道炎性反应进行有效评估，为哮喘疾病的诊断与治疗提供准确的参考价值。
목적：탐토호출기일양화담(FeNO)측정효천환자기도염성반응적림상개치。방법：2013년2월-2014년5월수치효천환자167례작위A조，병장기분위A1조(효천공제조)、A2조(부분공제조)여A3조(미공제조)。선택동기50례건강인원작위 B 조。대 A、B 량조환자적 FeNO 진행측정，대비량조 FEV1%、FEV1/FVC%적차이。결과：A 조환자FEV1%、FEV1/FVC%저우B조，차이유통계학의의(P＜0.05)。A조FeNO고우B조，차이유통계학의의(P＜0.05)。치료후，A1조여A2조환자FeNO치균현저적하강，단 A2조 FeNO 여 A3조、A1조비교，차이무통계학의의(P＞0.05)。결론：FeNO수평능구대효천환자기도염성반응진행유효평고，위효천질병적진단여치료제공준학적삼고개치。
Objective:To explore the clinical value of breath of nitric oxide(FeNO) determining the airway inflammatory reaction in patients with asthma.Methods:167 cases of patients with asthma from February 2013 to May 2014 as group A were divided into group A1 (the asthma controlled group),group A2 (the asthma controlled partial group) and group A3 (non control group).50 cases of healthy persons at the same period were as the group B.FeNO of the patients in groups A and B were determined.We compared the FEV1%,FEV1/FVC% of the two groups.Results:The FEV1%,FEV1/FVC% of patients in group A were lower than that of the group B,and the difference was statistically significant(P<0.05).The FeNO of group A was higher than that of the group B,and the difference was statistically significant(P<0.05).After treatment,the FeNO values of patients in group A1 and A2 were significantly declined,but there was no statistically significant difference of FeNO between group A2 and group A3,group A1(P>0.05). Conclusion:FeNO level could evaluate the airway inflammatory reaction in patients with asthma effectively,which could provide accurate reference value for the diagnosis and treatment of asthma disease.