传染病信息
傳染病信息
전염병신식
INFECTIOUS DISEASE INFORMATION
2014年
6期
373-376
,共4页
结核分枝杆菌%基因扩增%诊断
結覈分枝桿菌%基因擴增%診斷
결핵분지간균%기인확증%진단
Mycobacterium tuberculosis%gene amplification%diagnosis
结核分枝杆菌全基因组测序的完成,使得对结核分枝杆菌的认识进入分子水平,分子生物学和免疫学的发展为诊断新方法提供了技术平台,结核病实验室诊断技术得到快速发展。为帮助临床医生了解现有新技术,以便更好地应用,本文系统介绍现有结核病实验室诊断新技术的原理和临床应用特点。
結覈分枝桿菌全基因組測序的完成,使得對結覈分枝桿菌的認識進入分子水平,分子生物學和免疫學的髮展為診斷新方法提供瞭技術平檯,結覈病實驗室診斷技術得到快速髮展。為幫助臨床醫生瞭解現有新技術,以便更好地應用,本文繫統介紹現有結覈病實驗室診斷新技術的原理和臨床應用特點。
결핵분지간균전기인조측서적완성,사득대결핵분지간균적인식진입분자수평,분자생물학화면역학적발전위진단신방법제공료기술평태,결핵병실험실진단기술득도쾌속발전。위방조림상의생료해현유신기술,이편경호지응용,본문계통개소현유결핵병실험실진단신기술적원리화림상응용특점。
As whole-genome sequencing of Mycobacterium tuberculosis (Mtb) makes it possible to understand Mtb at the molecular level, and the development of molecular biology and immunology provides a technology platform for the new diagnostic assays, there has been a rapid development in novel diagnostic assays designed to detect Mtb and its drug resistance. To help clinicians understand the existing novel assays for better application, the authors introduce the principles and features of the existing novel diagnostic techniques of tuberculosis.