江西医药
江西醫藥
강서의약
JIANGXI MEDICAL JOURNAL
2014年
12期
1356-1359
,共4页
朱晓华%李岚%陈晨%朱双桂
硃曉華%李嵐%陳晨%硃雙桂
주효화%리람%진신%주쌍계
肺炎%病原体%儿童
肺炎%病原體%兒童
폐염%병원체%인동
Penumonia%Pathogen%Child
目的：分析冬春两季儿童肺炎感染病原学构成，为儿童肺炎的防治提供依据。方法以我院2013年11月-2014年4月肺炎患儿1943例为研究对象，进行痰培养、7种呼吸道病毒抗原及巨细胞病毒、肺炎支原体、肺炎衣原体检测，并对检测结果进行回顾性分析。结果1943例肺炎患儿中，病原阳性946例，阳性率48.7%，感染病原中病毒感染633例（66.9%），细菌感染195例（20.6%），支原体感染147例（15.5%），衣原体感染39例（4.1%），混合感染221例（23.4%）。病毒感染以呼吸道合胞病毒阳性率最高（62%），其次是巨细胞病毒（30.2%），流感/副流感（9.3%），腺病毒（5.5%）。细菌病原以肺炎链球菌最多见(12.5%)，其次为流感嗜血杆菌(9.8%)。1岁以下肺炎感染病原阳性率（64.8%）高于其他年龄段，以RSV、CMV感染为主，肺炎支原体是3岁以上儿童肺炎主要感染病原。重症肺炎218例，病原阳性146例，阳性率67.0%，以RSV感染为主，占62.2%，重症肺炎混合感染多，占24.3%。结论儿童肺炎发病以1岁以下儿童常见，病毒是冬春两季儿童肺炎最常见感染病原，且主要以RSV感染为主，多种病原混合感染率高，尤其是重症肺炎更为明显。
目的：分析鼕春兩季兒童肺炎感染病原學構成，為兒童肺炎的防治提供依據。方法以我院2013年11月-2014年4月肺炎患兒1943例為研究對象，進行痰培養、7種呼吸道病毒抗原及巨細胞病毒、肺炎支原體、肺炎衣原體檢測，併對檢測結果進行迴顧性分析。結果1943例肺炎患兒中，病原暘性946例，暘性率48.7%，感染病原中病毒感染633例（66.9%），細菌感染195例（20.6%），支原體感染147例（15.5%），衣原體感染39例（4.1%），混閤感染221例（23.4%）。病毒感染以呼吸道閤胞病毒暘性率最高（62%），其次是巨細胞病毒（30.2%），流感/副流感（9.3%），腺病毒（5.5%）。細菌病原以肺炎鏈毬菌最多見(12.5%)，其次為流感嗜血桿菌(9.8%)。1歲以下肺炎感染病原暘性率（64.8%）高于其他年齡段，以RSV、CMV感染為主，肺炎支原體是3歲以上兒童肺炎主要感染病原。重癥肺炎218例，病原暘性146例，暘性率67.0%，以RSV感染為主，佔62.2%，重癥肺炎混閤感染多，佔24.3%。結論兒童肺炎髮病以1歲以下兒童常見，病毒是鼕春兩季兒童肺炎最常見感染病原，且主要以RSV感染為主，多種病原混閤感染率高，尤其是重癥肺炎更為明顯。
목적：분석동춘량계인동폐염감염병원학구성，위인동폐염적방치제공의거。방법이아원2013년11월-2014년4월폐염환인1943례위연구대상，진행담배양、7충호흡도병독항원급거세포병독、폐염지원체、폐염의원체검측，병대검측결과진행회고성분석。결과1943례폐염환인중，병원양성946례，양성솔48.7%，감염병원중병독감염633례（66.9%），세균감염195례（20.6%），지원체감염147례（15.5%），의원체감염39례（4.1%），혼합감염221례（23.4%）。병독감염이호흡도합포병독양성솔최고（62%），기차시거세포병독（30.2%），류감/부류감（9.3%），선병독（5.5%）。세균병원이폐염련구균최다견(12.5%)，기차위류감기혈간균(9.8%)。1세이하폐염감염병원양성솔（64.8%）고우기타년령단，이RSV、CMV감염위주，폐염지원체시3세이상인동폐염주요감염병원。중증폐염218례，병원양성146례，양성솔67.0%，이RSV감염위주，점62.2%，중증폐염혼합감염다，점24.3%。결론인동폐염발병이1세이하인동상견，병독시동춘량계인동폐염최상견감염병원，차주요이RSV감염위주，다충병원혼합감염솔고，우기시중증폐염경위명현。
Objective To explore the etiology construction of children pneumonia and to provide a basis for the diagonsis and treatment. Methods Totally 1943 children with pneumonia in our hospital between Noveber 2013 and April 2014 were enrolled into the study.Sputum culture,detection of cytomegalovirus(CMV),mycoplasma pneumonia(MP),chlamydia pneumonia (CP) and i-dentification of seven kinds of respiratory viral antigents by direct immunoflurescence assay were conducted. The results were ana-lyzed retrospectively. Results 1943 cases were included in the study,with 946cases were positive infections (48.7%),Virus infec-tion for 633(66.9%),bacterial infection for 195(20.6%),MP for 147(15.5%)and CP for 39(4.1%),mixed infection for 221(23.4%). The respiratory syncytial virus (RSV) were the main pathogens for children pneumonia (62%). CMV(30.2%),influenza/parainfluen-zavirus(9.3%),adenovirus(5.5%). The top two of bacterial detection rates were Streptococcuspneumoniae(12.5%),Haemophilusin-fuenzae (9.8%). The infection rate was higher in children aged under one year (64.8%) than in those aged over one year. RSV and CMV were the main pathogens.MP infection was more common in children older than 3 years. The severe pneumonia was 218cas-es. The etiological detected rate was 67.0%(146/218). RSV was the main pathogen(62.2%). The mixed infection was common in the severe pneumonia(24.3%). Conclusion The children pneumonia is more common in infants less than 1 year. Virus infection is the most common pathogen,RSV is the main pathogen. Mixed infection rate of pathogens is high,especially in severe pneumonia.
