CAJ | 학술논문

目的：观察益气活血通脉汤对糖尿病周围神经病变患者生活质量的影响。方法：将60例患者随机分成治疗组30例与对照组30例，两组均给予饮食控制、合理运动处方；口服降糖药物或注射胰岛素控制血糖；对照组应用弥可保片治疗；治疗组在对照组基础上加用益气活血通脉汤治疗。两组均以30d为1个疗程，2个疗程评价疗效。观察两组中医临床证候疗效和治疗前后生活质量SF-36量表评分积分情况及不良反应变化。结果：两组中医临床证候疗效比较，治疗组与对照组总改善率分别为83.3%和60.0%（P＜0.05）；两组生活质量 SF-36量表评价积分，治疗组在总体健康、身体疼痛、活力、情感职能、精神健康、健康变化、生理职能等维度积分高于对照组（P＜0.05）。生理功能、社会功能积分比较，差异无统计学意义（P＞0.05）。两组患者不良反应症状均有不同程度加重，但治疗组明显低于对照组，差异有统计学意义（P＜0.05）。结论：益气活血通脉汤治疗糖尿病周围神经病变能改善中医临床症状，减轻不良反应，提高生活质量。
목적：관찰익기활혈통맥탕대당뇨병주위신경병변환자생활질량적영향。방법：장60례환자수궤분성치료조30례여대조조30례，량조균급여음식공제、합리운동처방；구복강당약물혹주사이도소공제혈당；대조조응용미가보편치료；치료조재대조조기출상가용익기활혈통맥탕치료。량조균이30d위1개료정，2개료정평개료효。관찰량조중의림상증후료효화치료전후생활질량SF-36량표평분적분정황급불량반응변화。결과：량조중의림상증후료효비교，치료조여대조조총개선솔분별위83.3%화60.0%（P＜0.05）；량조생활질량 SF-36량표평개적분，치료조재총체건강、신체동통、활력、정감직능、정신건강、건강변화、생리직능등유도적분고우대조조（P＜0.05）。생리공능、사회공능적분비교，차이무통계학의의（P＞0.05）。량조환자불량반응증상균유불동정도가중，단치료조명현저우대조조，차이유통계학의의（P＜0.05）。결론：익기활혈통맥탕치료당뇨병주위신경병변능개선중의림상증상，감경불량반응，제고생활질량。
Objective:To observe the impact of Yiqi Huoxue Tongmai Decoction on life quality of patients with diabetie peripheral neldropath-y. Methods:60 cases were randomly divided into the treatment group with 30 cases and the control group with 30 cases, patients in the two groups were controlled the diets and given exercises advices? orally taken hypoglycemic drugs or insulin to control blood glucose?patients in the control group were given Mecobalamin tablets?patients in the treatment group were given Yiqi Huoxue Tongmai Decoction based on the therapy for the control group. 30 days as a course, the assessment was given after two courses. Two groups were observed before and after treatment of TCM clinical syndrome efficacy and quality of life of SF-36 scale score points and adverse reaction of change. Results:The efficacy of the two groups were compared, the total improvement rate of the treatment group and the control group were respectively 83.3% and 60% (P<0.05)? the SF-36 quality of life scale of the two groups ,the overall health, body pain, vitality, emotional function, mental health, health and physical function changes the integral dimension of the treatment group were higher than those of the control group (P<0.05). Physiological function, social function integral comparison with no significant difference (P>0.05). Two groups of patients with adverse reactions to different degree increased, but the treatment group was significantly lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion:Yiqi Huoxue Tongmai Decoction in the treatment of diabetic peripheral neuropathy can improve clinical symptoms, reduce adverse reactions and improve the quality of life.