中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
36期
61-63
,共3页
糖尿病足%益气活血法%腔内治疗%再狭窄
糖尿病足%益氣活血法%腔內治療%再狹窄
당뇨병족%익기활혈법%강내치료%재협착
Diabetic foot%Yiqitongluo therapy%Endovascular treatment%Restenosis
目的：观察益气活血法预防糖尿病足腔内介入后再狭窄的临床疗效。方法：选择接受腔内治疗的糖尿病足患者370例，分为中药组与对照组，其中中药组185例，对照组185例。所有患者都给予抗血小板药物口服，中药组予益气活血法辨证加减口服中药。观察两组患者术后24个月间歇性跛行、静息痛、踝肱指数(ABI)、肢体再次溃疡或者坏疽及截肢等情况，并进行统计学分析。结果：24个月后，对照组中，1例患者膝下截肢，1例患者膝上截肢，1例患者出现左足趾溃疡，1例患者出现左足趾坏疽，中药组中仅出现1例左足趾坏疽。其中中药组再次出现间歇性跛行、静息痛症状均少于对照组（P<0.01），中药组ABI明显高于对照组（P<0.05）。结论：益气活血法可明显提高糖尿病足腔内治疗术后血管通畅率，改善肢体缺血症状。
目的：觀察益氣活血法預防糖尿病足腔內介入後再狹窄的臨床療效。方法：選擇接受腔內治療的糖尿病足患者370例，分為中藥組與對照組，其中中藥組185例，對照組185例。所有患者都給予抗血小闆藥物口服，中藥組予益氣活血法辨證加減口服中藥。觀察兩組患者術後24箇月間歇性跛行、靜息痛、踝肱指數(ABI)、肢體再次潰瘍或者壞疽及截肢等情況，併進行統計學分析。結果：24箇月後，對照組中，1例患者膝下截肢，1例患者膝上截肢，1例患者齣現左足趾潰瘍，1例患者齣現左足趾壞疽，中藥組中僅齣現1例左足趾壞疽。其中中藥組再次齣現間歇性跛行、靜息痛癥狀均少于對照組（P<0.01），中藥組ABI明顯高于對照組（P<0.05）。結論：益氣活血法可明顯提高糖尿病足腔內治療術後血管通暢率，改善肢體缺血癥狀。
목적：관찰익기활혈법예방당뇨병족강내개입후재협착적림상료효。방법：선택접수강내치료적당뇨병족환자370례，분위중약조여대조조，기중중약조185례，대조조185례。소유환자도급여항혈소판약물구복，중약조여익기활혈법변증가감구복중약。관찰량조환자술후24개월간헐성파행、정식통、과굉지수(ABI)、지체재차궤양혹자배저급절지등정황，병진행통계학분석。결과：24개월후，대조조중，1례환자슬하절지，1례환자슬상절지，1례환자출현좌족지궤양，1례환자출현좌족지배저，중약조중부출현1례좌족지배저。기중중약조재차출현간헐성파행、정식통증상균소우대조조（P<0.01），중약조ABI명현고우대조조（P<0.05）。결론：익기활혈법가명현제고당뇨병족강내치료술후혈관통창솔，개선지체결혈증상。
Objective:To observe the clinical effects of Yiqihuoxue therapy on preventing diabetic endovascular stent restenosis foot. Methods: 370 diabetic foot (DF) that successfully underwent endovascular therapy were randomly divided into two groups,the control group and the treatment group,185 in each group. Patients in the control group received antiplatelet treatment,while the treatment group was additionally Yiqihuoxue herbal medicine. Ankle brachial index (ABI),intermittent claudication,rest pain,ulcer,gangrene and the incidence of amputation in the following 24 months were recorded and observed in the two groups. Statistical analysis and comparison of observation was carried out with SPSS17.0. Results: After 24 months, in the control group, 1 patient received an above the knee amputation, 1 patient received an below the knee amputation, 1 patient had ulcer in his left foot,1 patient had gangrene with his left foot. In the treatment group, only 1 patient had gangrene in his left foot without amputation. Compared to the control group,the incidence rate of intermittent claudicating and the rest pain significantly decreased ( P<0.01)?ABI was significantly higher than that of the control group ( P<0.05).Conclusion:Yiqitongluo therapy can effectively improve ischemic symptoms of affected limbs through reducing the restenosis rate after endovascular therapy of Yiqitongluo herbal medicine.
