CAJ | 학술논문

目的：观察注射用鼠神经生长因子治疗脑出血的临床疗效。方法：选取脑出血患者78例，随机分为2组，对照组39例，应用胞二磷胆碱注射液0.5g，静滴，1次/d，观察组39例，应用注射用鼠神经生长因子18μg，肌内注射，1次/d，疗程4周，分别于治疗前及治疗后4周，对患者进行神经功能缺损评分及临床疗效评分。结果：治疗后，2组患者神经功能缺损评分较治疗前明显降低，差异有统计学意义（P＜0.05）。治疗后4周，观察组神经功能缺损评分较对照组明显降低，临床有效率明显增高，差异均有统计学意义（P＜0.05）。结论：注射用鼠神经生长因子可有效缓解脑出血患者的神经功能缺损。
목적：관찰주사용서신경생장인자치료뇌출혈적림상료효。방법：선취뇌출혈환자78례，수궤분위2조，대조조39례，응용포이린담감주사액0.5g，정적，1차/d，관찰조39례，응용주사용서신경생장인자18μg，기내주사，1차/d，료정4주，분별우치료전급치료후4주，대환자진행신경공능결손평분급림상료효평분。결과：치료후，2조환자신경공능결손평분교치료전명현강저，차이유통계학의의（P＜0.05）。치료후4주，관찰조신경공능결손평분교대조조명현강저，림상유효솔명현증고，차이균유통계학의의（P＜0.05）。결론：주사용서신경생장인자가유효완해뇌출혈환자적신경공능결손。
[ABSTRACT]Objective:To observe the curative effect of nerve growth factor (NGF) on cerebral hemorrhage. Methods: 78 patients with cerebral hemorrhage were randomly divided into 2 groups, the control group (39 cases) were received intravenous drip of 0.5g Citicoline injection, once a day, for 4 weeks.The observation group (39 cases)were received intramuscular injection of 18μg mouse NGF, once a day, for 4 weeks.Before and after treatment, nerve dysfunction and clinical curative effect were scored for the two groups. Results:The nerve dysfunction score was lower in the two groups after treatment than before treatment(P<0.05).The nerve dysfunction was lower whereas the clinical curative effect was higher in the obseration group than in the control group after 4 weeks treatment(P<0.05). Conclusion:NGF can effectively alleviate the nerve dysfunction of patients with cerebral hemorrhage.