中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2014年
12期
736-738
,共3页
女性%生殖系统感染%解脲脲原体%耐药变迁%抗药性,微生物
女性%生殖繫統感染%解脲脲原體%耐藥變遷%抗藥性,微生物
녀성%생식계통감염%해뇨뇨원체%내약변천%항약성,미생물
female%reproductive system infection%Ureaplasma urealyticum%change in drug resistance%drug re-sistance,microbial
目的：了解某中医医院女性生殖系统解脲脲原体（Uu）感染患者连续3年的耐药现状和变化趋势。方法对该中医医院2011年1月—2013年12月皮肤性病科和妇科门诊及住院女性患者送检的白带及宫颈分泌物标本分离的 Uu 的耐药性进行回顾性分析。结果共分离 Uu 327株，其3年耐药率，除多西环素（5．23％～6．12％）和交沙霉素（0～1．96％）较低外，其余抗菌药物均稍有增高，但差异无统计学意义（P ＞0．05）。Uu 对氧氟沙星、克拉霉素、司帕沙星的耐药率（42．11％～61．40％）较高，对交沙霉素、多西环素、美满霉素的耐药率（0～13．07％）较低，多药耐药现象较严重。结论该中医医院女性生殖系统感染患者分离的 Uu 耐药性较高。掌握 Uu耐药现状和变化趋势，对于疾病的治疗和控制多药耐药菌株的产生非常必要。
目的：瞭解某中醫醫院女性生殖繫統解脲脲原體（Uu）感染患者連續3年的耐藥現狀和變化趨勢。方法對該中醫醫院2011年1月—2013年12月皮膚性病科和婦科門診及住院女性患者送檢的白帶及宮頸分泌物標本分離的 Uu 的耐藥性進行迴顧性分析。結果共分離 Uu 327株，其3年耐藥率，除多西環素（5．23％～6．12％）和交沙黴素（0～1．96％）較低外，其餘抗菌藥物均稍有增高，但差異無統計學意義（P ＞0．05）。Uu 對氧氟沙星、剋拉黴素、司帕沙星的耐藥率（42．11％～61．40％）較高，對交沙黴素、多西環素、美滿黴素的耐藥率（0～13．07％）較低，多藥耐藥現象較嚴重。結論該中醫醫院女性生殖繫統感染患者分離的 Uu 耐藥性較高。掌握 Uu耐藥現狀和變化趨勢，對于疾病的治療和控製多藥耐藥菌株的產生非常必要。
목적：료해모중의의원녀성생식계통해뇨뇨원체（Uu）감염환자련속3년적내약현상화변화추세。방법대해중의의원2011년1월—2013년12월피부성병과화부과문진급주원녀성환자송검적백대급궁경분비물표본분리적 Uu 적내약성진행회고성분석。결과공분리 Uu 327주，기3년내약솔，제다서배소（5．23％～6．12％）화교사매소（0～1．96％）교저외，기여항균약물균초유증고，단차이무통계학의의（P ＞0．05）。Uu 대양불사성、극랍매소、사파사성적내약솔（42．11％～61．40％）교고，대교사매소、다서배소、미만매소적내약솔（0～13．07％）교저，다약내약현상교엄중。결론해중의의원녀성생식계통감염환자분리적 Uu 내약성교고。장악 Uu내약현상화변화추세，대우질병적치료화공제다약내약균주적산생비상필요。
Objective To investigate antimicrobial resistance and change trends ofUreaplasma urealyticum (Uu) from reproductive system of female patients at a traditional Chinese medicine hospital in three consecutive years. Methods Antimicrobial resistance of Uu isolated from gynaecology leucorrhea and cervical secretion specimens of patients of dermatology & sexually transmitted diseases department and gynaecology department from January 2011 to December 2013 were analyzed retrospectively.Results A total of 327 Uu strains were isolated,except resistance rates of Uu to doxycycline(5.23%-6.12%)and josamycin(0-1 .96%)remained at a relatively low level in three consecutive years,resistance rate to the other antimicrobials showed an upward trend year by year,but the difference was not significant (P >0.05).The resistance of Uu to ofloxacin,clarithromycin and sparfloxacin were relatively high(42.11 %-61 .40%),to josamycin,doxycycline and minocycline were lower(0-13.07%),and multidrug re-sistance was serious.Conclusion Antimicrobial resistanc of Uu isolated from reproductive system of female patients in this hospital is high.It is necessary to realize the status and change trends of antimicrobial resistance of Uu for the treatment of disease and control of the emergence of multidrug resistance pathogens.
