CAJ | 학술논문

目的：：优选抗感利咽糖浆的半仿生提取条件。方法：采用均匀设计法,在处方组成和用量、煎提温度、煎提用水量、过滤方法、离心时间、浓缩倍数等条件相同的情况下,用不同pH的水溶液提取方药,以连翘酯苷A、虎杖苷、黄芩苷、大黄素的含量及干浸膏的得率为指标,经过标准化处理,综合评价,优选该方药半仿生提取的工艺条件。结果：最佳的提取工艺为三煎用水的pH值依次为4.9、7.5、9.0,三煎总时间为2 h。结论：结合生产实际,确定三煎用水的pH值依次为5.0、7.5、9.0,3煎提取时间依次为1.0 h、0.5 h、0.5 h。
목적：：우선항감리인당장적반방생제취조건。방법：채용균균설계법,재처방조성화용량、전제온도、전제용수량、과려방법、리심시간、농축배수등조건상동적정황하,용불동pH적수용액제취방약,이련교지감A、호장감、황금감、대황소적함량급간침고적득솔위지표,경과표준화처리,종합평개,우선해방약반방생제취적공예조건。결과：최가적제취공예위삼전용수적pH치의차위4.9、7.5、9.0,삼전총시간위2 h。결론：결합생산실제,학정삼전용수적pH치의차위5.0、7.5、9.0,3전제취시간의차위1.0 h、0.5 h、0.5 h。
Objective: To optimize the conditions of semi-bionic extraction for Kanggan Liyan syrups. Methods: The samples were extracted by water with different pH values under the same conditions of formula composition and dosage, extraction temperature, filtration method, water voulme, centrifugal time and concentration multiple. The best conditions of the semi-bionic extraction for Kang-gan Liyan syrups were screened by uniform design with the content of forsythoside A, polydatin, baicalin and emodin and the dried ex-tract weight as the indices. Results:The best technical conditions were as follows:the pH value of water for the 1st, 2nd and 3rd de-coction was 4. 9, 7. 5 and 9. 0, respectively, and the total extraction time was 2h. Conclusion:According to the industrial production conditions, the pH value of water for the 1st, 2nd and 3rd decoction is 5. 0, 7. 5 and 9. 0 with the extraction time of 1h,0. 5h and 0. 5h, respectively.