缺血性脑中风中与内质网应激相关炎症反应研究进展
결혈성뇌중풍중여내질망응격상관염증반응연구진전
Research progress of inflammation reaction related to endoplasmic reticulum stress in ischemic endoplasmic reticulum stress
  • 万方数据
    中国药理学通报 중국약이학통보
    CHINESE PHARMACOLOGICAL BULLETIN
    2015年 1期 23-25,26 ,共4页

    黄志英%张晓旭%孙文利%陈畅%李德凤%方婧%付梅红%刘庆山%颜天华%李韶菁

    황지영%장효욱%손문리%진창%리덕봉%방청%부매홍%류경산%안천화%리소정

    缺血性脑中风%神经元损伤%微环境%内质网应激%炎症%相关信号通路 缺血性腦中風%神經元損傷%微環境%內質網應激%炎癥%相關信號通路
    결혈성뇌중풍%신경원손상%미배경%내질망응격%염증%상관신호통로
    ischemic stroke%neuron injury%microenvironment%endoplasmic reticulum stress%inflammation%related signal path-ways
    内质网是机体微环境的重要组成结构和功能单位，内质网内稳态失衡导致的内质网应激成为近年来的一个研究热点。该文主要针对内质网应激在缺血性脑中风中的作用及相关信号通路的研究进展进行综述，特别对内质网应激触发脑中风炎症反应的机制进行了系统的整理和总结，以期为缺血性中风的防治提供新的研究思路。
    내질망시궤체미배경적중요조성결구화공능단위，내질망내은태실형도치적내질망응격성위근년래적일개연구열점。해문주요침대내질망응격재결혈성뇌중풍중적작용급상관신호통로적연구진전진행종술，특별대내질망응격촉발뇌중풍염증반응적궤제진행료계통적정리화총결，이기위결혈성중풍적방치제공신적연구사로。
    Endoplasmic reticulum plays a key role in both basic structure formation and function performance of microenviron-ment. Endoplasmic reticulum homeostasis unbalance caused by endoplasmic reticulum stress has become a hot research topic in recent years. This paper focuses on the role of endoplasmic retic-ulum stress in ischemic stroke. Research progress of related sig-naling pathways were reviewed, especially mechanisms through which endoplasmic reticulum stress trigger the inflammatory reac-tion, so as to provide a new research method for prevention of is-chemic stroke.
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