CAJ | 학술논문

目的：探讨造血干细胞移植术后并发出血性膀胱炎患者中BK病毒的阳性率。方法：造血干细胞移植术后并发出血性膀胱炎患者30例作为观察组，30例健康成人为对照组，运用 PCR 检测技术检测尿中的 BK 病毒 DNA。结果：观察组26例检测出BK病毒DNA，病毒尿持续阳性中位时间7周(2～14周)，对照组均未检出BK病毒。结论：造血干细胞移植术后出血性膀胱炎是常见的并发症之一，在这些患者中病毒尿的发生率明显增高，BK病毒可能参与出血性膀胱炎的发病过程。
목적：탐토조혈간세포이식술후병발출혈성방광염환자중BK병독적양성솔。방법：조혈간세포이식술후병발출혈성방광염환자30례작위관찰조，30례건강성인위대조조，운용 PCR 검측기술검측뇨중적 BK 병독 DNA。결과：관찰조26례검측출BK병독DNA，병독뇨지속양성중위시간7주(2～14주)，대조조균미검출BK병독。결론：조혈간세포이식술후출혈성방광염시상견적병발증지일，재저사환자중병독뇨적발생솔명현증고，BK병독가능삼여출혈성방광염적발병과정。
Objective:To explore the BK virus positive in the urine of patients with hemorrhagic cystitis after hematopoietic stem cell transplantation.Methods:30 cases of hemorrhagic cystitis patients after hematopoietic stem cell transplantation were as the observation group,and 30 cases of healthy adults were as the control group.The BK virus DNA in urine were detected using PCR detection technology.Results:26 cases of the observation group had BK virus DNA detected.The median duration of positive virus urine was 7(2~14) weeks.The control group had no BK virus detected.Conclusion:Hemorrhagic cystitis is one of common complications after hematopoietic stem cell transplantation,in which the virus in the urine has significantly higher incidence,and BK virus may be involved in the pathogenesis of hemorrhagic cystitis process.