CAJ | 학술논문

目的：分析和探讨采用盐酸马布特罗片与盐酸丙卡特罗片治疗支气管哮喘的临床疗效及其安全性评价。方法选取呼吸内科2011年6月～2014年6月收治的72例支气管哮喘患者的临床资料，采用随机数表方法将所有患者随机分成两组，对照组36例患者在临床常规治疗方法的基础上给予盐酸丙卡特罗片进行治疗，观察组36例患者在常规治疗方法的基础上联合盐酸马布特罗片进行治疗，观察和比较两组患者的临床总有效率及其不良反应率。结果经过临床治疗，观察组36例患者的临床治疗总有效率为97.22%（35/36），对照组36例患者的临床治疗总有效率为83.33%（30/36），两组数据差异具有统计学意义（P＜0.05）；观察组患者的不良反应率为5.56%（2/36），对照组患者的不良反应率为2.78%（1/36），两组数据差异不具有统计学意义（P＞0.05）。结论本研究结果表明，采用盐酸马布特罗片治疗支气管哮喘临床效果明显，该用药方法能够有效缓解患者的主要临床症状，改善患者的内分泌功能及肺功能，有效调节患者机体的免疫系统功能，从而有效控制疾病，且该方法无明显临床不良反应，安全性好，因此值得临床推广使用。
목적：분석화탐토채용염산마포특라편여염산병잡특라편치료지기관효천적림상료효급기안전성평개。방법선취호흡내과2011년6월～2014년6월수치적72례지기관효천환자적림상자료，채용수궤수표방법장소유환자수궤분성량조，대조조36례환자재림상상규치료방법적기출상급여염산병잡특라편진행치료，관찰조36례환자재상규치료방법적기출상연합염산마포특라편진행치료，관찰화비교량조환자적림상총유효솔급기불량반응솔。결과경과림상치료，관찰조36례환자적림상치료총유효솔위97.22%（35/36），대조조36례환자적림상치료총유효솔위83.33%（30/36），량조수거차이구유통계학의의（P＜0.05）；관찰조환자적불량반응솔위5.56%（2/36），대조조환자적불량반응솔위2.78%（1/36），량조수거차이불구유통계학의의（P＞0.05）。결론본연구결과표명，채용염산마포특라편치료지기관효천림상효과명현，해용약방법능구유효완해환자적주요림상증상，개선환자적내분비공능급폐공능，유효조절환자궤체적면역계통공능，종이유효공제질병，차해방법무명현림상불량반응，안전성호，인차치득림상추엄사용。
Objective To analysis and discuss the respiratory department of internal medicine clinical use of mabuterol hydrochloride tablets and Procaterol Hydrochloride tablets treatment of bronchial asthma clinical curative effect and safety evaluation.Methods A retrospective analysis of our hospital respiratory department of internal medicine in June 2011 to June 2014, admitted 72 cases of bronchial asthma in patients with clinical data, using a random number table method all the patients were randomly divided into two groups, 36 cases in the control group were given the treatment of procaterol hydrochloride tablets in basic clinical routine method, 36 cases in the observation group were given the treatment of mabuterol hydrochloride tablets in basic clinical routine method, clinical observation and comparison of two groups of patients with total effective rate and adverse reaction rate.Results After the treatment, clinical observation of the treatment group of 36 patients with the total effective rate was 97.22%(35/36), controlled clinical treatment group of 36 patients with a total effective rate of 83.33%(30/36), the differences between the two groups of data significantly, with statistical significance(P<0.05); adverse reaction observation of clinical treatment in patients with the rate of 5.56%(2/36), controlled clinical patients in the treatment group the total effective rate was 2.78%(1/36), no significant difference between the two groups of data, was not statistically significant(P>0.05).Conclusions The results of this study show that respiratory department of internal medicine clinical use of mabuterol hydrochloride tablets in the treatment of bronchial asthma clinical effect, the medication method can effectively alleviate the main clinical symptoms of patients, improve patient within the sub function and secretion of pulmonary function, immune system function in patients with effective regulation of the body, so as to effectively control the disease. No obvious clinical adverse reactions and the method, the security is good, so it is worthy of clinical use.