CAJ | 학술논문

肝衰竭是指多种原因导致肝细胞合成、解毒、排泄和生物转化等功能严重障碍，出现以凝血功能障碍、黄疸、肝性脑病、腹水等为主要表现的一组临床症候群，由于肝衰竭疾病凶险，因此预后判断对于其诊治具有重要意义。近年来对于肝衰竭预后判定报道屡见不鲜，回顾了有关血清学及综合模型的研究及应用，为临床肝衰竭患者合理治疗提供参考。
간쇠갈시지다충원인도치간세포합성、해독、배설화생물전화등공능엄중장애，출현이응혈공능장애、황달、간성뇌병、복수등위주요표현적일조림상증후군，유우간쇠갈질병흉험，인차예후판단대우기진치구유중요의의。근년래대우간쇠갈예후판정보도루견불선，회고료유관혈청학급종합모형적연구급응용，위림상간쇠갈환자합리치료제공삼고。
Liver failure is a clinical syndrome with severe disorders of liver cells for biosynthesis,detoxication,excretion,and biological transformation,which presents with coagulation disorders,jaundice,hepatic encephalopathy,and ascites.Liver failure progresses rapidly, so the prediction of clinical outcome is significant for the diagnosis and treatment.In recent years,there have been numerous reports on the prediction of clinical outcome in patients with liver failure.The study and application of serological and comprehensive models are reviewed, which provides a reference for the rational therapy for liver failure patients.