CAJ | 학술논문

中医药防治慢性乙型肝炎（CHB）积累了丰富经验，但尚存在一些不足之处，如随机对照的临床研究开展不够、客观化的疗效评价指标重视程度欠缺等。在今后的临床防治工作中，应紧密结合CHB免疫发病机制的研究进展，充分发挥中医药调整人体功能状态包括免疫功能状态的特色和优势，开展中医药调控CHB免疫应答的临床研究和转化医学研究，进一步提高临床疗效；在总结临床实践经验时，除了注重患者的症状，还要积极应用生化学、病毒学、病理学等替代结局指标，以提高疗效评价的客观性；在临床研究中，尽可能采用随机对照的临床研究方法，以提高中医药临床疗效的公认性。充分发挥我国CHB防治的中西医结合优势，必将造福广大患者。
중의약방치만성을형간염（CHB）적루료봉부경험，단상존재일사불족지처，여수궤대조적림상연구개전불구、객관화적료효평개지표중시정도흠결등。재금후적림상방치공작중，응긴밀결합CHB면역발병궤제적연구진전，충분발휘중의약조정인체공능상태포괄면역공능상태적특색화우세，개전중의약조공CHB면역응답적림상연구화전화의학연구，진일보제고림상료효；재총결림상실천경험시，제료주중환자적증상，환요적겁응용생화학、병독학、병이학등체대결국지표，이제고료효평개적객관성；재림상연구중，진가능채용수궤대조적림상연구방법，이제고중의약림상료효적공인성。충분발휘아국CHB방치적중서의결합우세，필장조복엄대환자。
Abundant experience has been accumulated when it comes to the traditional Chinese medicine (TCM)prevention and treatment of chronic hepatitis B (CHB).However,there still exist some deficiencies such as insufficient randomized controlled trials (RCTs)and lack of attention to objective indices for therapeutic evaluation.Therefore,future clinical prevention and treatment should be tied closely to the re-search progress in the immune pathogenesis of CHB and give full play to the characteristics and advantages of TCM in modulating the func-tional status (including immunity)of human body.Moreover,clinical and translational research on the TCM regulation of immune response in CHB should be carried out to further improve clinical therapeutic effect.In addition,biochemistry,virology,and pathology should be ap-plied actively in place of outcomes while paying attention to the symptoms of patients in an effort to improve the objectivity of therapeutic e-valuation when summarizing clinical practice experience.Furthermore,RCTs should be employed as much as possible to enhance global rec-ognition of the therapeutic effect of TCM treatment.And there is no doubt that bringing the advantages of integrated traditional Chinese and Western medicine therapy into full play will benefit a huge number of patients.