CAJ | 학술논문

目的：分析我院呼吸道感染患儿肺炎支原体(Mycoplasma pneumoniae，MP)感染情况及其对常用抗生素的耐药性。方法选取2011年1月至2013年12月我科治疗的289例呼吸道感染患儿为研究对象，记录静脉血检测MP抗体IgM阳性率，并对阳性患儿进行痰培养鉴定，观察并记录药敏试验结果。结果289例急性呼吸道感染患儿咽拭子支原体培养检测阳性75例(26.0%)，低于1岁、1~3岁、3~6岁、6~12岁呼吸道感染患儿支原体培养阳性率差异均无统计学意义(P>0.05)。MP对强力霉素、美满霉素、阿奇霉素、左氧氟沙星、司帕沙星敏感性较高，而对交沙霉素、克拉霉素、罗红霉素、氧氟沙星呈不同程度的耐药。结论呼吸道感染患儿MP感染率较高，应进行痰培养及药敏试验，选用敏感抗生素，减少耐药株出现。
목적：분석아원호흡도감염환인폐염지원체(Mycoplasma pneumoniae，MP)감염정황급기대상용항생소적내약성。방법선취2011년1월지2013년12월아과치료적289례호흡도감염환인위연구대상，기록정맥혈검측MP항체IgM양성솔，병대양성환인진행담배양감정，관찰병기록약민시험결과。결과289례급성호흡도감염환인인식자지원체배양검측양성75례(26.0%)，저우1세、1~3세、3~6세、6~12세호흡도감염환인지원체배양양성솔차이균무통계학의의(P>0.05)。MP대강력매소、미만매소、아기매소、좌양불사성、사파사성민감성교고，이대교사매소、극랍매소、라홍매소、양불사성정불동정도적내약。결론호흡도감염환인MP감염솔교고，응진행담배양급약민시험，선용민감항생소，감소내약주출현。
Objective To investigate the distribution of children Mycoplasma pneumonia (MP) infection in our hospital,and to analyze the drug resistance of MP. Methods From January, 2011 to December 2013, 289 chil-dren with respiratory tract infection were selected in our hospital. MP-IgM test and sputum samples were collected for MP cultivation identification and drug sensitive test was conducted. Results Among 289 children with respiratory in-fection, 75 cases of MP-IgM test were positive with a positive rate of 26.0%. There was no significant difference in the positive rate of MP Ig-M among children of≤1 years old, 1~3 years old, 3~6 years old, and 6~12 years old (P>0.05). Drug sensitive test showed that MP was sensitive to doxycycline, minocycline, azithromycin, levofloxacin, and sparfloxacin and insensitive to josamycin, clarithromycin, roxithromycin and ofloxacin. Conclusion With higher in-cidence of children MP infection, MP-IgM test, sputum samples culture and drug sensitivity test should be taken in time to reduce the drug resistance.