海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2015年
1期
43-45
,共3页
张文渊%朱兆钧%蔡永明%殷亚磊%李景青
張文淵%硃兆鈞%蔡永明%慇亞磊%李景青
장문연%주조균%채영명%은아뢰%리경청
糠酸莫米松%儿童%变应性鼻炎%菌群
糠痠莫米鬆%兒童%變應性鼻炎%菌群
강산막미송%인동%변응성비염%균군
Furoic acid mo betamethasone%Children%Allergic rhinitis%Flora
目的：探讨糠酸莫米松鼻喷雾剂对儿童变应性鼻炎鼻腔黏液菌群的影响，并观察其临床疗效。方法选取我院门诊治疗的49例变应性鼻炎儿童患者作为治疗组，给予糠酸莫米松治疗，同时对其治疗前后鼻腔黏液的菌群分布情况进行检测，另设立48例未患变应性鼻炎的正常儿童为对照组进行比较。结果治疗组患者经糠酸莫米松治疗后鼻部症状、眼部症状、呼吸道症状评分均较治疗前明显降低(P<0.05)，治疗组治疗后鼻部症状、眼部症状、呼吸道症状得分均高于对照组(P<0.05)。经检测发现，对照组病原菌检出率为91.7%，其中需氧菌和真菌各占82.4%和17.6%，而治疗组治疗前病原菌检出率为91.8%，需氧菌和真菌各占79.6%和20.4%，治疗后病原菌检出率为93.9%，其中需氧菌和真菌各占85.4%和14.6%，其中需氧菌以凝固酶阴性葡萄球菌居首位，真菌则以曲霉菌居首位。但对照组与治疗组治疗前以及治疗组治疗前后比较差异均无统计学意义(P>0.05)。结论糠酸莫米松鼻喷雾剂治疗儿童变应性鼻炎对改善患儿的临床症状有较好效果，但对鼻腔黏液菌群不产生明显影响。
目的：探討糠痠莫米鬆鼻噴霧劑對兒童變應性鼻炎鼻腔黏液菌群的影響，併觀察其臨床療效。方法選取我院門診治療的49例變應性鼻炎兒童患者作為治療組，給予糠痠莫米鬆治療，同時對其治療前後鼻腔黏液的菌群分佈情況進行檢測，另設立48例未患變應性鼻炎的正常兒童為對照組進行比較。結果治療組患者經糠痠莫米鬆治療後鼻部癥狀、眼部癥狀、呼吸道癥狀評分均較治療前明顯降低(P<0.05)，治療組治療後鼻部癥狀、眼部癥狀、呼吸道癥狀得分均高于對照組(P<0.05)。經檢測髮現，對照組病原菌檢齣率為91.7%，其中需氧菌和真菌各佔82.4%和17.6%，而治療組治療前病原菌檢齣率為91.8%，需氧菌和真菌各佔79.6%和20.4%，治療後病原菌檢齣率為93.9%，其中需氧菌和真菌各佔85.4%和14.6%，其中需氧菌以凝固酶陰性葡萄毬菌居首位，真菌則以麯黴菌居首位。但對照組與治療組治療前以及治療組治療前後比較差異均無統計學意義(P>0.05)。結論糠痠莫米鬆鼻噴霧劑治療兒童變應性鼻炎對改善患兒的臨床癥狀有較好效果，但對鼻腔黏液菌群不產生明顯影響。
목적：탐토강산막미송비분무제대인동변응성비염비강점액균군적영향，병관찰기림상료효。방법선취아원문진치료적49례변응성비염인동환자작위치료조，급여강산막미송치료，동시대기치료전후비강점액적균군분포정황진행검측，령설립48례미환변응성비염적정상인동위대조조진행비교。결과치료조환자경강산막미송치료후비부증상、안부증상、호흡도증상평분균교치료전명현강저(P<0.05)，치료조치료후비부증상、안부증상、호흡도증상득분균고우대조조(P<0.05)。경검측발현，대조조병원균검출솔위91.7%，기중수양균화진균각점82.4%화17.6%，이치료조치료전병원균검출솔위91.8%，수양균화진균각점79.6%화20.4%，치료후병원균검출솔위93.9%，기중수양균화진균각점85.4%화14.6%，기중수양균이응고매음성포도구균거수위，진균칙이곡매균거수위。단대조조여치료조치료전이급치료조치료전후비교차이균무통계학의의(P>0.05)。결론강산막미송비분무제치료인동변응성비염대개선환인적림상증상유교호효과，단대비강점액균군불산생명현영향。
Objective To discuss the influence of furoic acid mo betamethasone nasal spray on children al-lergic rhinitis nasal mucus flora, and to observe its clinical curative effect. Methods Forty-nine patients with allergic rhinitis in children were selected as the treatment group and given furoic acid mo betamethasone nasal spray. The bac-terial flora distribution of nasal mucus flora before and after the treatment were tested. The results were compared with those of 48 healthy children without allergic rhinitis (the control group). Results The nasal symptoms, eye symp-toms, respiratory tract symptom scores in the treatment group after treatment were significantly lower than those before treatment (P<0.05), and the nasal symptoms, eye symptoms, respiratory symptoms score in the treatment group after treatment were significantly higher than those in the control group (P<0.05). After testing, the pathogen detection rate in the control group was 91.7%(with aerobic bacteria and fungi accounting for 82.4%and 17.6%). The pathogen detection rate in the treatment group was 91.8%before treatment (aerobic bacteria and fungi accounting for 79.6%and 20.4%) and 93.9%after treatment (aerobic bacteria and fungi accounting for 85.4%and 14.6%), with coagulase negative staphy-lococcus aureus for aerobe and aspergillus for fungus mainly. There was no statistically significant difference between the two groups before treatment, and in the treatment group before and after treatment (P>0.05). Conclusion Furoic acid mo betamethasone nasal spray has good effect on improving the patient's clinical symptoms to treat children of al-lergic rhinitis, but it has no significant effect on nasal mucus flora.
