CAJ | 학술논문

目的：观察腹腔镜直肠癌根治术后患者尿动力学及消化道功能状态的变化。方法选取2011年9月至2014年1月于本院进行根治性手术治疗的74例直肠癌患者为研究对象，将其随机分为对照组(开腹手术组)和观察组(腹腔镜手术组)各37例，检测并比较两组患者手术前后的尿动力学变化及血清胃肠激素和小肠传输功能。结果观察组手术后3d及7d的尿动力学指标最大尿流率、最大排尿压及排尿期逼尿肌收缩压均大于对照组，残余尿量则小于对照组，血清胃肠激素GAS、MTL、VIP、SS水平均高于对照组，以上指标比较差异均有统计学意义(P<0.05)；术后1 d及3 d的小肠传输功能相关指标AUC及PC显著高于对照组，PT低于对照组，差异均有统计学意义(P<0.05)。结论腹腔镜直肠癌根治术对患者尿动力学及消化道功能状态的不良影响明显小于开腹手术患者，且患者术后的上述各项指标恢复相对较快。
목적：관찰복강경직장암근치술후환자뇨동역학급소화도공능상태적변화。방법선취2011년9월지2014년1월우본원진행근치성수술치료적74례직장암환자위연구대상，장기수궤분위대조조(개복수술조)화관찰조(복강경수술조)각37례，검측병비교량조환자수술전후적뇨동역학변화급혈청위장격소화소장전수공능。결과관찰조수술후3d급7d적뇨동역학지표최대뇨류솔、최대배뇨압급배뇨기핍뇨기수축압균대우대조조，잔여뇨량칙소우대조조，혈청위장격소GAS、MTL、VIP、SS수평균고우대조조，이상지표비교차이균유통계학의의(P<0.05)；술후1 d급3 d적소장전수공능상관지표AUC급PC현저고우대조조，PT저우대조조，차이균유통계학의의(P<0.05)。결론복강경직장암근치술대환자뇨동역학급소화도공능상태적불량영향명현소우개복수술환자，차환자술후적상술각항지표회복상대교쾌。
Objective To observe the changes in the urodynamics and digestive tract function of patients af-ter laparoscopic radical resection of rectal cancer. Methods Seventy-four patients with rectal cancer in our hospital from September 2011 to January 2014 were selected as study subjects, which were randomly divided into control group (open operation group, n=37) and observation group (laparoscopic operation group, n=37). Then the urodynam-ic changes, serum gastrointestinal hormones, and small intestine transmission function of two groups before and after the operation were detected and compared. Results 3 d and 7 d after operation, the urodynamic indices such as maxi-mum flow rate, maximum voiding detrusor voiding pressure and systolic blood pressure of the observation group were significantly greater than control group, while the residual urine volume was significantly less than the control group, and the serum levels of gastrointestinal hormone such as GAS, MTL, VIP, SS levels were significantly higher than the control group, P<0.05. 1 d and 3 d after operation, intestinal transport functions related indicators (AUC and PC) were significantly higher control group, and PT was significantly lower than the control group, P<0.05. Conclusion The bad influence of laparoscopic radical resection of rectal cancer on the urodynamics and digestive tract function of pa-tients are significantly smaller than that of open operation, with relatively rapid recovery of the related indices.