中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
2期
35-36
,共2页
洛赛克%消化性溃疡%西咪替丁
洛賽剋%消化性潰瘍%西咪替丁
락새극%소화성궤양%서미체정
Losec%Peptic ulcer%Cimetidine
目的：探讨洛赛克治疗消化性溃疡的临床疗效。方法：2013年12月-2014年9月收治消化性溃疡患者146例，随机分成观察组和对照组，各73例。两组均给予阿莫西林胶囊1.0 g/次，2次/d，克拉霉素0.5 g/次，2次/d，于饭后服用。对照组在此基础上加西咪替丁0.2～0.4 g/次，4次/d，餐后及睡前服。观察组在此基础上加用洛赛克20 mg/次，2次/d，两组均连续治疗2周。结果：观察组痊愈40例，显效25例，好转6例，无效2例，总有效率97.3%；对照组痊愈33例，显效22例，好转9例，无效9例，总有效率87.7%；两组总有效率比较差异有统计学意义(P＜0.05)。观察组止血时间(14.2±1.1)h，均控制出血，对照组止血时间(37.7±3.5)h，控制出血例数20例，两组比较差异有统计学意义(P＜0.05)。结论：洛赛克治疗消化性溃疡疗效显著，值得推广。
目的：探討洛賽剋治療消化性潰瘍的臨床療效。方法：2013年12月-2014年9月收治消化性潰瘍患者146例，隨機分成觀察組和對照組，各73例。兩組均給予阿莫西林膠囊1.0 g/次，2次/d，剋拉黴素0.5 g/次，2次/d，于飯後服用。對照組在此基礎上加西咪替丁0.2～0.4 g/次，4次/d，餐後及睡前服。觀察組在此基礎上加用洛賽剋20 mg/次，2次/d，兩組均連續治療2週。結果：觀察組痊愈40例，顯效25例，好轉6例，無效2例，總有效率97.3%；對照組痊愈33例，顯效22例，好轉9例，無效9例，總有效率87.7%；兩組總有效率比較差異有統計學意義(P＜0.05)。觀察組止血時間(14.2±1.1)h，均控製齣血，對照組止血時間(37.7±3.5)h，控製齣血例數20例，兩組比較差異有統計學意義(P＜0.05)。結論：洛賽剋治療消化性潰瘍療效顯著，值得推廣。
목적：탐토락새극치료소화성궤양적림상료효。방법：2013년12월-2014년9월수치소화성궤양환자146례，수궤분성관찰조화대조조，각73례。량조균급여아막서림효낭1.0 g/차，2차/d，극랍매소0.5 g/차，2차/d，우반후복용。대조조재차기출상가서미체정0.2～0.4 g/차，4차/d，찬후급수전복。관찰조재차기출상가용락새극20 mg/차，2차/d，량조균련속치료2주。결과：관찰조전유40례，현효25례，호전6례，무효2례，총유효솔97.3%；대조조전유33례，현효22례，호전9례，무효9례，총유효솔87.7%；량조총유효솔비교차이유통계학의의(P＜0.05)。관찰조지혈시간(14.2±1.1)h，균공제출혈，대조조지혈시간(37.7±3.5)h，공제출혈례수20례，량조비교차이유통계학의의(P＜0.05)。결론：락새극치료소화성궤양료효현저，치득추엄。
Objective:To investigate the clinical effect of losec in the treatment of peptic ulcer.Methods:146 patients with peptic ulcer were selected from December 2013 to September 2014.They were randomly divided into the observation group and the control group with 73 cases in each.The two groups were given amoxicillin capsules 1.0 g/time,2 times/d,clarithromycin 0.5 g/time, 2 times/d,after meals.The control group were given cimetidine 0.2~0.4 g/time based on this,4 times/d,after meals and before the bedtime.The observation group used losec 20 mg/time based on this,2 times/d.Two groups were treated continuously for 2 weeks. Results:In the observation group,40 cases were recovered;25 cases were markedly effective;6 cases were improved;2 cases were ineffective;the total efficiency was 97.3%.In the control group,33 cases were cured;22 cases were markedly effective;9 cases were improved;9 cases were ineffective;the total efficiency was 87.7%.The difference of total efficiency of two groups was statistically significant(P<0.05).The bleeding time of the observation group was(14.2±1.1)h,and all bleeding of them were controlled;the bleeding time of the control group was(37.7 ± 3.5)h,and 20 cases of patients bleeding were controlled;the difference was statistically significant(P<0.05).Conclusion:The therapeutic effect of losec in the treatment of peptic ulcer is significantly,so it is worthy of promotion.
