临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2015年
2期
300-302,303
,共4页
血小板平均体积%C-反应蛋白%社区获得性肺炎%预后%危险因素
血小闆平均體積%C-反應蛋白%社區穫得性肺炎%預後%危險因素
혈소판평균체적%C-반응단백%사구획득성폐염%예후%위험인소
mean platelet volume%C-reactive protein%community acquired pneumonia%prognosis%risk fac-tor
目的：探讨入血小板平均体积（MPV）与老年社区获得性肺炎（CAP）近期预后的关系。方法选取2012年1月至2014年6月我院收治的108例老年CAP患者为研究对象，检测所有患者入院时的MPV、CRP、血常规中WBC计数及中性粒细胞百分比（PMN％）以及血气指标，并记录患者的APACHEⅡ评分等；按照老年CAP患者不同病情程度以及预后情况进行相关分组，比较各组间的MPV、CRP、WBC计数、PMN％及血气指标的差异，并应用Logistic回归模型分析老年CAP患者近期预后的危险因素。结果与非重症组比较，重症组MPV、CRP、WBC计数、PMN％、Plt计数、APACHEⅡ评分显著增高（P＜0.05）、PaO2及氧合指数降低（P＜0.05）；与生存组比较，死亡组亦MPV升高（P＜0.05）；MPV＞11.215 fl的患者分组中的重症CAP患者及30 d死亡患者的比例明显高于MPV≤11.215 fl分组患者（P＜0.05）；经pearson相关分析显示：MPV与WBC计数、CRP、PMN％、APACHEⅡ评分呈正相关，而与氧合指数呈负相关；多因素Logistic 回归分析显示：MPV（OR＝1.605，P＜0.05）是老年CAP患者近期预后不良的高危因素。结论血小板平均体积与老年CAP患者病情程度及近期预后密切相关，高水平MPV可能是老年CAP患者近期预后不良的高危因素。
目的：探討入血小闆平均體積（MPV）與老年社區穫得性肺炎（CAP）近期預後的關繫。方法選取2012年1月至2014年6月我院收治的108例老年CAP患者為研究對象，檢測所有患者入院時的MPV、CRP、血常規中WBC計數及中性粒細胞百分比（PMN％）以及血氣指標，併記錄患者的APACHEⅡ評分等；按照老年CAP患者不同病情程度以及預後情況進行相關分組，比較各組間的MPV、CRP、WBC計數、PMN％及血氣指標的差異，併應用Logistic迴歸模型分析老年CAP患者近期預後的危險因素。結果與非重癥組比較，重癥組MPV、CRP、WBC計數、PMN％、Plt計數、APACHEⅡ評分顯著增高（P＜0.05）、PaO2及氧閤指數降低（P＜0.05）；與生存組比較，死亡組亦MPV升高（P＜0.05）；MPV＞11.215 fl的患者分組中的重癥CAP患者及30 d死亡患者的比例明顯高于MPV≤11.215 fl分組患者（P＜0.05）；經pearson相關分析顯示：MPV與WBC計數、CRP、PMN％、APACHEⅡ評分呈正相關，而與氧閤指數呈負相關；多因素Logistic 迴歸分析顯示：MPV（OR＝1.605，P＜0.05）是老年CAP患者近期預後不良的高危因素。結論血小闆平均體積與老年CAP患者病情程度及近期預後密切相關，高水平MPV可能是老年CAP患者近期預後不良的高危因素。
목적：탐토입혈소판평균체적（MPV）여노년사구획득성폐염（CAP）근기예후적관계。방법선취2012년1월지2014년6월아원수치적108례노년CAP환자위연구대상，검측소유환자입원시적MPV、CRP、혈상규중WBC계수급중성립세포백분비（PMN％）이급혈기지표，병기록환자적APACHEⅡ평분등；안조노년CAP환자불동병정정도이급예후정황진행상관분조，비교각조간적MPV、CRP、WBC계수、PMN％급혈기지표적차이，병응용Logistic회귀모형분석노년CAP환자근기예후적위험인소。결과여비중증조비교，중증조MPV、CRP、WBC계수、PMN％、Plt계수、APACHEⅡ평분현저증고（P＜0.05）、PaO2급양합지수강저（P＜0.05）；여생존조비교，사망조역MPV승고（P＜0.05）；MPV＞11.215 fl적환자분조중적중증CAP환자급30 d사망환자적비례명현고우MPV≤11.215 fl분조환자（P＜0.05）；경pearson상관분석현시：MPV여WBC계수、CRP、PMN％、APACHEⅡ평분정정상관，이여양합지수정부상관；다인소Logistic 회귀분석현시：MPV（OR＝1.605，P＜0.05）시노년CAP환자근기예후불량적고위인소。결론혈소판평균체적여노년CAP환자병정정도급근기예후밀절상관，고수평MPV가능시노년CAP환자근기예후불량적고위인소。
Objective To explore the correlation between mean platelet volume and recent prognosis of eld-erly patients with community acquired pneumonia.Methods 1 08 CAP patients were selected as research subjects, and their MPV,CRP,blood routine and blood gas analysis were detected.The score of APACHEⅡ was also recor-ded.All patients were divided into different groups according to different severity and recent prognosis.The risk fac-tors influencing recent prognosis were assessed by logistic regression analysis.Results Compared with the non-se-vere group,the levels of MPV,CRP,WBC,PMN%,Plt and APACHEⅡscore increased and the levels of PaO2 and oxygenation index decreased obviously in the severe group (P<0.05 ).Compared with the survival group,the level of MPV increased significantly in the death group (P<0.05 ).There were more severe patients and higher mortality while the level of MPV was higher than 1 1 .21 5 fl.Pearson correlation analysis showed that the level of MPV was pos-itively correlated with WBC,CRP,PMN%,and APACHEⅡscore,and it was negatively correlated with oxygenation index.Multi-factor logistic regression analysis showed that MPV was independent predictors of recent prognosis in CAP patients (OR=1.605 ,P<0.05 ).Conclusion MPV is closely related to the severity and prognosis of elderly patients with CAP,and the level of MPV is an high risk for recent prognosis of elderly patients with CAP.
