CAJ | 학술논문

目的：探讨支气管动脉栓塞化疗（BACE）联合I125植入治疗晚期肺癌的临床疗效。方法选择39例经BACE治疗后支气管动脉闭塞，再次于30天左右联合CT引导下经皮穿刺植入I125粒子治疗，41例BACE治疗作为对照组。结果本组CR17例，PR19例，NC 3例，总有效率（CR＋PR）为92.3％。3个月生存率94.2％，6个月生存率91.3％，一年生存率83.2％。对照组CR12例，PR21例，NC 8例，总有效率（CR＋PR）80.4％，3个月生存率93.1％，6个月生存率88.4％，一年生存率72.6％。结论 BACE联合CT引导下经皮穿刺植入I125粒子治疗晚期肺癌微创安全，较单纯BACE治疗近中期疗效明显提高，晚期肺癌BACE联合I125综合治疗值得临床推广。
목적：탐토지기관동맥전새화료（BACE）연합I125식입치료만기폐암적림상료효。방법선택39례경BACE치료후지기관동맥폐새，재차우30천좌우연합CT인도하경피천자식입I125입자치료，41례BACE치료작위대조조。결과본조CR17례，PR19례，NC 3례，총유효솔（CR＋PR）위92.3％。3개월생존솔94.2％，6개월생존솔91.3％，일년생존솔83.2％。대조조CR12례，PR21례，NC 8례，총유효솔（CR＋PR）80.4％，3개월생존솔93.1％，6개월생존솔88.4％，일년생존솔72.6％。결론 BACE연합CT인도하경피천자식입I125입자치료만기폐암미창안전，교단순BACE치료근중기료효명현제고，만기폐암BACE연합I125종합치료치득림상추엄。
Objective To observe the clinical effect of bronchial artery occlusion induced by BACE com-bined with I1 25 seed implantation in the treatment of advanced lung cancer.Methods 39 cases of bronchial artery occlusion after BACE treatment were selected,and they were implanted with I1 25 seed again in 30 days under CT guided percutaneous.Another 41 cases of BACE were treated as the control group.Results There were 1 7 cases of CR,1 9 cases of PR,and 3 cases of NC in the study group.The total response rate (CR+PR)was 92.3% in the study group. The 3-month survival rate was 94.2%,the 6-month survival rate was 91.3%,and the 1-year survival rate was 83.2% in the study group.There were 1 2 cases of CR,21 cases of PR,and 8 cases of NC in the control group. The total response rate (CR+PR)was 80.4%in the control group.The 3-month survival rate was 93.1%, the 6-month survival rate was 88.4%,and the 1-year survival rate was 72.6% in the control group.Conclusion BACE combined with I1 25 seed implantation under CT guided percutaneous is minimally invasive safe and shows higher total effective rate in the treatment of advanced lung cancer.