CAJ | 학술논문

目的：应用中文版FACT-L4．0和WHO DASⅡ（他评版）两种国际生存质量量表作为测定工具，评价榄香稀注射液对治疗非小细胞肺癌患者生存质量的影响，同时以传统的临床疗效评价指标作为参照。方法将200例非小细胞肺癌患者分为观察组及对照组各100例，两组均给予吉西他滨单药化疗：吉西他滨（健泽）1000 mg／m2，静脉滴注30分钟，第1、8、15天，28天为1个周期，连用4个周期。观察组使用榄香稀注射液从化疗的第1天开始用生理盐水500 ml＋榄香稀注射液50 ml静脉滴注，1天1次，连用15天，使用4个周期后评价疗效。结果经过4个周期治疗后，观察组患者在生理功能、情绪功能、角色功能、社会活动参与功能及总体健康情况等多个领域评分高于单纯化疗组，两组比较差异有统计学意义（P＜0.05），两组患者治疗近期疗效比较差异无显著性（P＞0.05）。结论榄香稀注射液可改善非小细胞肺癌患者机体状态，提高患者生存质量。
목적：응용중문판FACT-L4．0화WHO DASⅡ（타평판）량충국제생존질량량표작위측정공구，평개람향희주사액대치료비소세포폐암환자생존질량적영향，동시이전통적림상료효평개지표작위삼조。방법장200례비소세포폐암환자분위관찰조급대조조각100례，량조균급여길서타빈단약화료：길서타빈（건택）1000 mg／m2，정맥적주30분종，제1、8、15천，28천위1개주기，련용4개주기。관찰조사용람향희주사액종화료적제1천개시용생리염수500 ml＋람향희주사액50 ml정맥적주，1천1차，련용15천，사용4개주기후평개료효。결과경과4개주기치료후，관찰조환자재생리공능、정서공능、각색공능、사회활동삼여공능급총체건강정황등다개영역평분고우단순화료조，량조비교차이유통계학의의（P＜0.05），량조환자치료근기료효비교차이무현저성（P＞0.05）。결론람향희주사액가개선비소세포폐암환자궤체상태，제고환자생존질량。
Objective To evaluate the effect of elemi dilute injection on quality of life of patients with non-small cell lung cancer by two different methods,FACT-DAS Ⅱ L4.0 and WHO.Methods 200 cases of non-small cell lung cancer patients were randomly divided into the observation group and the control group,1 00 cases in each group.All patients were given gemcitabine single-agent chemotherapy,and the observation group was additionally given elemi dilute injection.The total treatment lasted 4 cycles,28 days per cycle.Results The scores of physio-logical function,emotional function,social activities involved function and general healthy condition were obviously higher in the observation group than in the control group (P<0.05 ).There was no significance in short-term cura-tive effect between the two groups (P>0.05 ).Conclusion Elemi dilute injection can improve the body status and quality of life in the treatment of patients with non-small cell lung cancer.