CAJ | 학술논문

目的：探讨强化血糖控制治疗肺结核合并糖尿病患者的效果并进行分析。方法100例肺结核合并2型糖尿病患者分成研究组与对照组，每组各50例，两组患者均给予2～3HRZE／9～10HRE 方案治疗，均给予糖尿病饮食、适量运动、健康教育。研究组给予胰岛素皮下注射控制血糖，对照组给予口服降糖药物控制血糖。结果研究组临床疗效高于对照组（98.0％ vs 90.0％，P＜0.05），痰菌阴转率、病灶吸收好转率、空洞闭合率均明显高于对照组（P＜0.05）；研究组血沉、T淋巴细胞亚群改善情况亦优于对照组（P＜0.05）。结论血糖水平与肺结核化学治疗效果关系密切，强化血糖控制有益于肺结核合并糖尿病患者的治疗。
목적：탐토강화혈당공제치료폐결핵합병당뇨병환자적효과병진행분석。방법100례폐결핵합병2형당뇨병환자분성연구조여대조조，매조각50례，량조환자균급여2～3HRZE／9～10HRE 방안치료，균급여당뇨병음식、괄량운동、건강교육。연구조급여이도소피하주사공제혈당，대조조급여구복강당약물공제혈당。결과연구조림상료효고우대조조（98.0％ vs 90.0％，P＜0.05），담균음전솔、병조흡수호전솔、공동폐합솔균명현고우대조조（P＜0.05）；연구조혈침、T림파세포아군개선정황역우우대조조（P＜0.05）。결론혈당수평여폐결핵화학치료효과관계밀절，강화혈당공제유익우폐결핵합병당뇨병환자적치료。
Objective To explore and analyze the curative effect of intensive blood glucose control in the treatment of tuberculosis patients complicated with diabetes.Methods 1 00 tuberculosis patients complicated with diabetes were randomly divided into the research group (n=50)and the control group (n=50).All patients were given 2~3HRZE /9~1 0HRE therapy,such as the control of diet,the moderate exercise and education of healthy. The research group was given insulin subcutaneous injection to control blood glucose,while the control group were given the oral hypoglycemic drugs to control blood glucose.Results The curative effect was better in the research group than in the control group (98.0%vs 90.0%,P<0.05 ).The improvement of sputum conversion rate,lesions absorption rate,cavity closure rate was more pronounced in the research group than in the control group (P<0.05 ). The improvement of ESR and thymus-dependent lymphocyte in the research group was also superior to the control group (P<0.05 ).Conclusion The blood glucose level is closely related to the therapeutic effect of tuberculosis. The intensive blood glucose control is benefit to the treatment of tuberculosis patients complicated with diabetes.