CAJ | 학술논문

RGC-32(response gene to complement-32)是一种重要的补体应答分子,同时也参与了许多其他生物学功能.近来的研究发现RGC-32为细胞周期G2/M检测点关键调控分子,在细胞周期精细调控过程中发挥重要作用,并参与细胞增殖分化、再生修复、炎症反应、肿瘤形成等多种生物学过程.但RGC-32对细胞周期确切的调控机制有待阐明.该文就RGC-32基因及其生物学功能、细胞周期调控以及两者之间的调控关系等作一简要综述.
RGC-32(response gene to complement-32)시일충중요적보체응답분자,동시야삼여료허다기타생물학공능.근래적연구발현RGC-32위세포주기G2/M검측점관건조공분자,재세포주기정세조공과정중발휘중요작용,병삼여세포증식분화、재생수복、염증반응、종류형성등다충생물학과정.단RGC-32대세포주기학절적조공궤제유대천명.해문취RGC-32기인급기생물학공능、세포주기조공이급량자지간적조공관계등작일간요종술.
As one of the important response gene to complement,response gene to complement-32 (RGC-32) simultaneously involves in many other biological functions.Recent studies have shown that RGC-32 was one of the critical regulatory factors at the G2/M check point in the cell cycles and involved in the cell cycle regulation.The expression products of RGC-32 gene play the key roles in cell proliferation,differentiation,inflammation,tumor metastasis and other processes.However,it has not been clarified in its biological mechanisms of regulation in cell cycle.This article takes a brief review about RGC-32 on its gene structure,biological functions,regulation of cell cycle,and the relationship of cell cycle regulation which involves in RGC-32.